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1,4-Naphthalenedione,5-hydroxy-2-methyl- cas no:481-42-5

Synonyms: 1,4-Naphthoquinone,5-hydroxy-2-methyl- (7CI,8CI);Plumbagin (6CI);2-Methyl-5-hydroxy-1,4-naphthalenedione;2-Methyl-5-hydroxy-1,4-naphthoquinone;2-Methyljuglone;5-Hydroxy-2-methyl-1,4-naphthoquinone;NSC 236613;NSC 688284;Plumbagine;Plumbagone;

Identification
Name1,4-Naphthalenedione,5-hydroxy-2-methyl-
CAS481-42-5
Synonyms1,4-Naphthoquinone,5-hydroxy-2-methyl- (7CI,8CI);Plumbagin (6CI);2-Methyl-5-hydroxy-1,4-naphthalenedione;2-Methyl-5-hydroxy-1,4-naphthoquinone;2-Methyljuglone;5-Hydroxy-2-methyl-1,4-naphthoquinone;NSC 236613;NSC 688284;Plumbagine;Plumbagone;
EINECS(EC#)207-569-6
Molecular FormulaC11H8O3
Molecular Weight188.19
Chemical Properties
Appearanceorange crystalline powder or crystals
refractive index1.63
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T
Risk R23/24/25
Safety

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes ToxicT
Risk Statements 25-34 
R25 :Toxic if swallowed. 
R34:Causes burns.
Safety Statements 22-26-36/37/39-45
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 2923 8/PG 2
WGK Germany 3
RTECS QL8500000
Hazard Note Toxic
HazardClass 6.1(a)
PackingGroup II
 

 


Toxicity
1.    

mma-sat 100 µg/plate

    MUREAV    Mutation Research. 124 (1983),25.
2.    

mmo-esc 500 µmol/L

    JOBAAY    Journal of Bacteriology. 164 (1985),1309.
3.    

orl-rat LD50:65 mg/kg

    IJMRAQ    Indian Journal of Medical Research. 65 (1977),829.
4.    

orl-mus LD50:16 mg/kg

    IJEBA6    Indian Journal of Experimental Biology. 18 (1980),876.
5.    

ipr-mus LD50:5 mg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 8 (1)(1982),73.

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Hangzhou J&H Chemical Co., Ltd
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