Phosphorothioic acid,O-(4-bromo-2,5-dichlorophenyl) O,O-diethyl ester cas no:4824-78-6

NamePhosphorothioic acid,O-(4-bromo-2,5-dichlorophenyl) O,O-diethyl ester
CAS4824-78-6
SynonymsBromophosA; Bromophos-ethyl; Ethyl bromophos; Filariol; Filariol 60; Nexagan; Nexagan G;O,O-Diethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate;O-(4-Bromo-2,5-dichlorophenyl) O,O-diethyl phosphorothioate; OMS 659
EINECS(EC#)225-399-0
Molecular FormulaC10H12 Br Cl2 O3 P S
Molecular Weight394.06

refractive indexn20/D 1.565
storage temp0-6°C

Hazardclass6.1(a)

Hazard T,N
Risk 21-25-50/53
Safety

Hazard Codes: TT,NN
Risk Statementsof Ethyl bromophos (CAS NO.4824-78-6): 21-25-50/53 
R21:Harmful in contact with skin. R25 :Toxic if swallowed. R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 28-36/37-45-60-61 
S28:After contact with skin, wash immediately with plenty of soap-suds. S36/37:Wear suitable protective clothing and gloves. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60:This material and its container must be disposed of as hazardous waste. S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 3018
RTECS: TE7000000
HazardClass: 6.1(a)
PackingGroup: II
Poison by ingestion. Moderately toxic by skin contact and inhalation. An insecticide. When heated to decomposition it emits very toxic fumes of Br⁻, PO_x, SO_x, and Cl⁻. See also CHLOROPHENOLS.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	20500ug/kg (20.5mg/kg)		Journal de Toxicologie Clinique et Experimentale. Vol. 6(3), Pg. 175, 1986.
chicken	LD50	oral	600mg/kg (600mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
dog	LD50	oral	360mg/kg (360mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
domestic animals - goat/sheep	LDLo	oral	125mg/kg (125mg/kg)		Pesticide Manual. Vol. 1, Pg. 49, 1968.
guinea pig	LDLo	oral	100mg/kg (100mg/kg)		Pesticide Manual. Vol. 1, Pg. 49, 1968.
mouse	LD50	intraperitoneal	25mg/kg (25mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
mouse	LD50	oral	210mg/kg (210mg/kg)		Farm Chemicals Handbook. Vol. -, Pg. C51, 1991.
quail	LD50	oral	200mg/kg (200mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
rabbit	LD50	oral	28mg/kg (28mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
rabbit	LD50	skin	500mg/kg (500mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
rat	LCLo	inhalation	16600ppb/2H (16.6ppm)		"Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
rat	LD50	intraperitoneal	60mg/kg (60mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 25, Pg. 180, 1973.
rat	LD50	oral	52mg/kg (52mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 36, 1978.
rat	LD50	skin	1gm/kg (1000mg/kg)		World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat	LD50	unreported	238mg/kg (238mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 335, 1971.