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Cytisine cas no:485-35-8

Synonyms: (-)-cytisine ; SOPHORINE; 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one; 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin; 1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-, (1R)-; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-, (1R-cis)-; 2-a)(1,5)diazocin-8-one,1,2,3,4,5,6-hexahydro-5-methano-8h-pyrido(1; 5)diazocin-8-one,1,2,3,4,5,6-hexahydro-5-methano-8h-pyrido((1r)-2-a)(1

Identification
NameCytisine
CAS485-35-8
Synonyms(-)-cytisine ; SOPHORINE; 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one; 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin; 1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-, (1R)-; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-, (1R-cis)-; 2-a)(1,5)diazocin-8-one,1,2,3,4,5,6-hexahydro-5-methano-8h-pyrido(1; 5)diazocin-8-one,1,2,3,4,5,6-hexahydro-5-methano-8h-pyrido((1r)-2-a)(1
EINECS(EC#)207-616-0
Molecular FormulaC11H14N2O
Molecular Weight190.24
Chemical Properties
AppearanceOff-White to Tan Crystalline Solid
storage tempStore at RT
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T:Toxic
Risk R25;R36/37/38
Safety

Poison by ingestion, intravenous and intraperitoneal routes. A toxin found in some plants. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:?ToxicT
Risk Statements: 25-36/37/38?
R25 :Toxic if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-28-36/37-45?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: HA4025000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

scu-rat LDLo:20?mg/kg

??? 85IXA4 ?? Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif Bovet, D., andF. Bovet-Nitti,New York, NY.:?S. Karger,1948,589.
2. ???

orl-mus LD50:101?mg/kg

??? BJPCBM ?? British Journal of Pharmacology. 35 (1969),161.
3. ???

ipr-mus LD50:9400?μg/kg

??? BJPCBM ?? British Journal of Pharmacology. 35 (1969),161.
4. ???

ivn-mus LD50:1730?μg/kg

??? BJPCBM ?? British Journal of Pharmacology. 35 (1969),161.
5. ???

inv-cat LD50:400?μg/kg

??? ITOBAO ?? Izvestiya Akademii Nauk Tadzhikskoi SSR, Otdelenie Biologicheskikh Nauk.(2),(1978),104.

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