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1H-Indol-5-ol,3-[2-(dimethylamino)ethyl]- cas no:487-93-4

Synonyms: Bufotenine(6CI); Indol-5-ol, 3-[2-(dimethylamino)ethyl]- (7CI,8CI);3-(2-Dimethylaminoethyl)indol-5-ol; 3-(b-Dimethylaminoethyl)-5-hydroxyindole;5-Hydroxy-N,N-dimethyltryptamine; Bufotenin; Cinobufotenine; Dimethylserotonin;Mappin; Mappine; N,N-Dimethyl-5-hydroxytryptamine; N,N-Dimethylserotonin; NSC89593

Identification
Name1H-Indol-5-ol,3-[2-(dimethylamino)ethyl]-
CAS487-93-4
SynonymsBufotenine(6CI); Indol-5-ol, 3-[2-(dimethylamino)ethyl]- (7CI,8CI);3-(2-Dimethylaminoethyl)indol-5-ol; 3-(b-Dimethylaminoethyl)-5-hydroxyindole;5-Hydroxy-N,N-dimethyltryptamine; Bufotenin; Cinobufotenine; Dimethylserotonin;Mappin; Mappine; N,N-Dimethyl-5-hydroxytryptamine; N,N-Dimethylserotonin; NSC89593
EINECS(EC#)207-667-9
Molecular FormulaC12H16 N2 O
Molecular Weight204.30
Chemical Properties
refractive index1.646
storage tempRefrigerator, Under Inert Atmosphere
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

Poison by intraperitoneal route. Human systemic effects with very small amounts taken by intravenous route: psychotropic effects. A modified natural neurotransmitter. When heated to decomposition it emits toxic fumes of NOx
RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo parenteral 2500mg/kg (2500mg/kg) cardiac: other changes Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 86, Pg. 138, 1920.
human TDLo intravenous 57ug/kg (0.057mg/kg) peripheral nerve and sensation: sensory change involving peripheral nerve lungs, thorax, or respiration: other changes gastrointestinal: other changes Science. Vol. 123, Pg. 886, 1956.
mouse LD50 intraperitoneal 290mg/kg (290mg/kg)   Psychopharmacologia Vol. 16, Pg. 385, 1970.
mouse LD50 intravenous 25mg/kg (25mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 144, 1968.

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