Pachycarpine cas no:492-08-0
Synonyms: PACHYCARPINE;(1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane;(7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine;d-Sparteine;Sparteine d-isomer
NamePachycarpine
CAS492-08-0
SynonymsPACHYCARPINE;(1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane;(7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine;d-Sparteine;Sparteine d-isomer
Molecular FormulaC15H26N2
Molecular Weight234.38
Safety
Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
89100ug/kg (89.1mg/kg) |
behavioral: tremor behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea |
Shaanxi Xinyiyao. Shaanxi New Medical. Vol. 11(6), Pg. 53, 1982. |
| mouse |
LD50 |
intravenous |
26mg/kg (26mg/kg) |
|
"Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich, D.A., Moscow, First Moscow Medical Institute, 1967Vol. -, Pg. 175, 1967. |
| mouse |
LD50 |
subcutaneous |
90mg/kg (90mg/kg) |
behavioral: muscle contraction or spasticity) lungs, thorax, or respiration: dyspnea
|
Farmakologiya i Toksikologiya Vol. 21(5), Pg. 46, 1958. |
