Nornicotine cas no:494-97-3
Synonyms: NORNICOTINE, DL-(RG);(S)-2-(3-Pyridyl)pyrrolidine;(s)-nicotin;dl-Norcitine;l-Nor-nicotine;Nicotine, 1'-demethyl-, (S)-;Nornicotin;Pyridine, 3-(2-pyrrolidinyl)-, (S)-
NameNornicotine
CAS494-97-3
SynonymsNORNICOTINE, DL-(RG);(S)-2-(3-Pyridyl)pyrrolidine;(s)-nicotin;dl-Norcitine;l-Nor-nicotine;Nicotine, 1'-demethyl-, (S)-;Nornicotin;Pyridine, 3-(2-pyrrolidinyl)-, (S)-
Molecular FormulaC9H12N2
Molecular Weight148.20498
refractive index1.536
storage tempRefrigerator, under inert atmosphere
Safety
Poison by intraperitoneal and intravenous routes. About 1/3 the toxicity of nicotine. Causes faintness, prostration, muscular weakness, severe nausea, vomiting, diarrhea, and collapse without convulsions. An insecticide. When heated to decomposition it emits highly toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
14660ug/kg (14.66mg/kg) |
|
Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 8, Pg. 69, 1957. |
| mouse |
LD50 |
intravenous |
3409ug/kg (3.409mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 82, 1946. |
| rabbit |
LD50 |
intraperitoneal |
> 13700ug/kg (13.7mg/kg) |
|
Proceedings of the Society for Experimental Biology and Medicine. Vol. 58, Pg. 231, 1945. |
| rabbit |
LD50 |
intravenous |
3mg/kg (3mg/kg) |
|
Proceedings of the Society for Experimental Biology and Medicine. Vol. 58, Pg. 231, 1945. |
| rat |
LDLo |
intraperitoneal |
23500ug/kg (23.5mg/kg) |
|
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 1061, 1989. |