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Guanidine hydrochloride cas no:50-01-1

Synonyms: Guanidine,monohydrochloride (8CI,9CI);Buffer AL;Guanidine chloride;Guanidinehydrochloride;Guanidinium chloride;Guanidinium hydrochloride;

Identification
NameGuanidine hydrochloride
CAS50-01-1
SynonymsGuanidine,monohydrochloride (8CI,9CI);Buffer AL;Guanidine chloride;Guanidinehydrochloride;Guanidinium chloride;Guanidinium hydrochloride;
EINECS(EC#)200-002-3
Molecular FormulaCH5N3.HCl
Molecular Weight95.53
Chemical Properties
AppearanceWhite cryst. powder
refractive indexn20/D 1.465
storage tempStore at RT.
Sensitive Hygroscopic
Safety Data

Hazard Xn:Harmful
Risk R22;R36/38
Safety

Safety Information of Guanidine hydrochloride (50-01-1):
Hazard Codes: Xn,Xi
Risk Statements: 22-36/38?
22:? Harmful if swallowed
36:? Irritating to the eyes???
38:? Irritating to the skin?
Safety Statements: 26-36-22
22:? Do not breathe dust
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:? Wear suitable protective clothing


HS Code 29252000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo subcutaneous 200mg/kg (200mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1352, 1935.
guinea pig LDLo intraarterial 500mg/kg (500mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo intravenous 500mg/kg (500mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1352, 1935.
mammal (species unspecified) LDLo oral 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene. Vol. 13, Pg. 87, 1931.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg) ? National Technical Information Service. Vol. AD277-689,
mouse LD50 oral 571mg/kg (571mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: IRRITABILITY
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 598, 1993.
rabbit LD skin > 2gm/kg (2000mg/kg) ? Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 596, 1993.
rat LD50 oral 475mg/kg (475mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: EXCITEMENT

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
National Technical Information Service. Vol. AD-A165-747,
rat LDLo subcutaneous 404mg/kg (404mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 28, Pg. 251, 1926.

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