Vitamin D2 cas no:50-14-6
Synonyms: (3beta)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol; Metadee; Doral; Drisdol; Ergocalciferol; Ergocalciferolum; Ergorone; Ergosterol, activated; Ertron; Fortodyl; Geltabs; Hi-deratol; Hytakerol; Infron; Mulsiferol; Mykostin; Oleovitamin D2; Ostelin; Radiostol; Radsterin; Rocaltrol; Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Shock-ferol; Viosterol; Vitamin D; Vitavel-D; 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Arthin; Diactol; Divit urto; BUCO-D; Calciferol; Calciferolum; Calciferon 2; Calderol; Condacaps; Condol; Crtron; Crystallina; Daral; Davitamon D; Davitin; Decaps; Dee-osterol; Deratol; Dee-ron; Dee-ronal; Detalup; DHT; Deltalin;
NameVitamin D2
CAS50-14-6
Synonyms(3beta)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol; Metadee; Doral; Drisdol; Ergocalciferol; Ergocalciferolum; Ergorone; Ergosterol, activated; Ertron; Fortodyl; Geltabs; Hi-deratol; Hytakerol; Infron; Mulsiferol; Mykostin; Oleovitamin D2; Ostelin; Radiostol; Radsterin; Rocaltrol; Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Shock-ferol; Viosterol; Vitamin D; Vitavel-D; 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Arthin; Diactol; Divit urto; BUCO-D; Calciferol; Calciferolum; Calciferon 2; Calderol; Condacaps; Condol; Crtron; Crystallina; Daral; Davitamon D; Davitin; Decaps; Dee-osterol; Deratol; Dee-ron; Dee-ronal; Detalup; DHT; Deltalin;
EINECS(EC#)200-014-9
Molecular FormulaC28H44O
Molecular Weight396.65
Appearanceodorless white crystals
alpha82 o (C=3, IN ACETONE 25 oC)
refractive index1.53
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard T+:Verytoxic;
Risk R24/25;R26;R48/25
Safety
Poison by ingestion, intraperitoneal, intravenous, and intramuscular routes. An experimental teratogen. Human systemic effects by ingestion: anorexia, nausea or vomiting, and weight loss. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?Xn,T+,T
Risk Statements: 22-48/25-26-24/25-40-23/24/25?
R22: Harmful if swallowed.?
R48: Danger of serious damage to health by prolonged exposure.?
R25: Toxic if swallowed.?
R26: Very toxic by inhalation.?
R40: Limited evidence of a carcinogenic effect.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 28-36/37-45-28A-36-26-36/37/39-22?
S28: After contact with skin, wash immediately with plenty of soap-suds.?
S36/37: Wear suitable protective clothing and gloves.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S22: Do not breathe dust.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: KE1050000
F: 1-8-10
HazardClass: 6.1(a)
PackingGroup of Ergocalciferol (CAS NO.50-14-6): II
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
cat |
LDLo |
oral |
5mg/kg (5mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 128, 1982. |
dog |
LDLo |
intramuscular |
5mg/kg (5mg/kg) |
? |
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
dog |
LDLo |
intraperitoneal |
10mg/kg (10mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FLUID INTAKE
GASTROINTESTINAL: NAUSEA OR VOMITING |
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
dog |
LDLo |
intravenous |
5mg/kg (5mg/kg) |
? |
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
dog |
LDLo |
oral |
4mg/kg (4mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
GASTROINTESTINAL: NAUSEA OR VOMITING |
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
duck |
LD50 |
oral |
> 2gm/kg (2000mg/kg) |
? |
Defense des Vegetaux. Vol. 43(255-256), Pg. 14, 1989. |
guinea pig |
LDLo |
oral |
40mg/kg (40mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 128, 1982. |
mouse |
LD50 |
oral |
23700ug/kg (23.7mg/kg) |
? |
Pesticide Manual. Vol. 9, Pg. 115, 1991. |
rat |
LD50 |
oral |
10mg/kg (10mg/kg) |
? |
"Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 3, Pg. 132, 1986. |
women |
TDLo |
oral |
12600ug/kg/72 (12.6mg/kg) |
BEHAVIORAL: ANOREXIA (HUMAN
GASTROINTESTINAL: NAUSEA OR VOMITING |
Lancet. Vol. 1, Pg. 1164, 1980. |