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Vitamin D2 cas no:50-14-6

Synonyms: (3beta)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol; Metadee; Doral; Drisdol; Ergocalciferol; Ergocalciferolum; Ergorone; Ergosterol, activated; Ertron; Fortodyl; Geltabs; Hi-deratol; Hytakerol; Infron; Mulsiferol; Mykostin; Oleovitamin D2; Ostelin; Radiostol; Radsterin; Rocaltrol; Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Shock-ferol; Viosterol; Vitamin D; Vitavel-D; 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Arthin; Diactol; Divit urto; BUCO-D; Calciferol; Calciferolum; Calciferon 2; Calderol; Condacaps; Condol; Crtron; Crystallina; Daral; Davitamon D; Davitin; Decaps; Dee-osterol; Deratol; Dee-ron; Dee-ronal; Detalup; DHT; Deltalin;

Identification
NameVitamin D2
CAS50-14-6
Synonyms(3beta)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol; Metadee; Doral; Drisdol; Ergocalciferol; Ergocalciferolum; Ergorone; Ergosterol, activated; Ertron; Fortodyl; Geltabs; Hi-deratol; Hytakerol; Infron; Mulsiferol; Mykostin; Oleovitamin D2; Ostelin; Radiostol; Radsterin; Rocaltrol; Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Shock-ferol; Viosterol; Vitamin D; Vitavel-D; 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-; Arthin; Diactol; Divit urto; BUCO-D; Calciferol; Calciferolum; Calciferon 2; Calderol; Condacaps; Condol; Crtron; Crystallina; Daral; Davitamon D; Davitin; Decaps; Dee-osterol; Deratol; Dee-ron; Dee-ronal; Detalup; DHT; Deltalin;
EINECS(EC#)200-014-9
Molecular FormulaC28H44O
Molecular Weight396.65
Chemical Properties
Appearanceodorless white crystals
alpha82 o (C=3, IN ACETONE 25 oC)
refractive index1.53
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T+:Verytoxic;
Risk R24/25;R26;R48/25
Safety

Poison by ingestion, intraperitoneal, intravenous, and intramuscular routes. An experimental teratogen. Human systemic effects by ingestion: anorexia, nausea or vomiting, and weight loss. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?Xn,T+,T
Risk Statements: 22-48/25-26-24/25-40-23/24/25?
R22: Harmful if swallowed.?
R48: Danger of serious damage to health by prolonged exposure.?
R25: Toxic if swallowed.?
R26: Very toxic by inhalation.?
R40: Limited evidence of a carcinogenic effect.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 28-36/37-45-28A-36-26-36/37/39-22?
S28: After contact with skin, wash immediately with plenty of soap-suds.?
S36/37: Wear suitable protective clothing and gloves.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S22: Do not breathe dust.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: KE1050000
F: 1-8-10
HazardClass: 6.1(a)
PackingGroup of Ergocalciferol (CAS NO.50-14-6): II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 5mg/kg (5mg/kg) ? Drugs in Japan Vol. 6, Pg. 128, 1982.
dog LDLo intramuscular 5mg/kg (5mg/kg) ? Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950.
dog LDLo intraperitoneal 10mg/kg (10mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: FLUID INTAKE

GASTROINTESTINAL: NAUSEA OR VOMITING
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950.
dog LDLo intravenous 5mg/kg (5mg/kg) ? Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950.
dog LDLo oral 4mg/kg (4mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: NAUSEA OR VOMITING
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950.
duck LD50 oral > 2gm/kg (2000mg/kg) ? Defense des Vegetaux. Vol. 43(255-256), Pg. 14, 1989.
guinea pig LDLo oral 40mg/kg (40mg/kg) ? Drugs in Japan Vol. 6, Pg. 128, 1982.
mouse LD50 oral 23700ug/kg (23.7mg/kg) ? Pesticide Manual. Vol. 9, Pg. 115, 1991.
rat LD50 oral 10mg/kg (10mg/kg) ? "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 3, Pg. 132, 1986.
women TDLo oral 12600ug/kg/72 (12.6mg/kg) BEHAVIORAL: ANOREXIA (HUMAN

GASTROINTESTINAL: NAUSEA OR VOMITING
Lancet. Vol. 1, Pg. 1164, 1980.

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