1,2-Butanediol,2-phenyl-, 1-carbamate cas no:50-19-1

Name1,2-Butanediol,2-phenyl-, 1-carbamate
CAS50-19-1
SynonymsCarbamic acid, b-ethyl-b-hydroxyphenethyl ester (7CI);2-Hydroxy-2-phenylbutyl carbamate;AL 0361;Hydroxyphenamate;Listica;NSC108034;Oxyfenamate;Oxyphenamate;P 301;b-Ethyl-b-hydroxyphenethyl carbamate
EINECS(EC#)200-017-5
Molecular FormulaC11H15 N O3
Molecular Weight209.27

refractive index1.545

Safety Moderately toxic by ingestion and intravenous routes. A minor tranquilizer. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

EK2450000

CHEMICAL NAME :

1,2-Butanediol, 2-phenyl-, 1-carbamate

CAS REGISTRY NUMBER :

50-19-1

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C11-H15-N-O3

MOLECULAR WEIGHT :

209.27

WISWESSER LINE NOTATION :

ZVO1XQ2&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

607 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,394,1972

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

830 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

425 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

233 gm/kg/52W-I

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Related to Chronic Data - death

REFERENCE :

DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961