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Estriol cas no:50-27-1

Synonyms: 1,3,5-Oestratriene-3beta,16alpha,17beta-triol;NSC-12169;1,3,5(10)-Estratriene-3,16-alpha,17beta-triol;(16.alpha.,17.beta.)-Oestra-1,3,5(10)-triene-3,16,17-triol;16.alpha.-Hydroxyestradiol;16.alpha.,17.beta.-Estriol;1,3,5-Estratriene-3beta,16alpha,17beta-triol;1,3, 5(10)-Estratriene-3,16.alpha., 17.beta.-triol;Estra-1,3,5(10)-triene-3,16,17-triol,(16R,17a)-;Estra-1,3,5(10)-trien-3, 16.alpha., 17.beta.-triol;16-alpha-Hydroxyoestradiol;16.alpha.-Estriol;16alpha-Hydroxy-17beta-estradiol;Triovex;Ovestrion;Oestra-1,3,5(10)-triene-3,16alpha,17beta-triol;3, 16.alpha.,17.beta.-Estriol;Synapause;Klimoral;Folicular hormone;16-alpha-Hydroxyestradiol;3,16.alpha., 17.beta.-Trihydroxy-1,3,5(10)-estratriene;Hemostyptanon;Estra-1,3,5(10)-triene-3,16,17-triol, (16alpha,17beta)-;Estra-1,3,5(10)-trien-3,16alpha,17beta-triol;Estriolo [Italian];Tridestrin;Estra-1,3,5(10)-trien-3,16.alpha., 17.beta.-triol;3,16-alpha,17-beta-Oestriol;3,16-alpha,17-beta-Estriol;Oestra-1,3,5(10)-triene-3,16.alpha., 17.beta.-triol;Aacifemine;16.alpha.,17.beta.-Oestriol;Deuslon-A;Oestratriol;3,16alpha,17beta-Trihydroxy-1,3,5(10)-estratriene;3,16.alpha., 17.beta.-Trihydroxy-.delta.-1,3,5-oestratriene;16.alpha.-Hydroxyoestradiol;3,16alpha,17beta-Trihydroxy-delta-1,3,5-oestratriene;A 13610;Oestriolum;Trihydroxyoestrin;Holin V;Thulol;Triodurin;Orestin;Estra-1,3,5(10)-triene-3,16.alpha.,17.beta.-triol;Oestriol [Steroidal oestrogens];Overstin;Orgastyptin;Ovestin;Estriel;(16alpha,17beta)-estra-1,3,5(10)-triene-3,16,17-triol;Theelol;Stiptanon;(16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol;

Identification
NameEstriol
CAS50-27-1
Synonyms1,3,5-Oestratriene-3beta,16alpha,17beta-triol;NSC-12169;1,3,5(10)-Estratriene-3,16-alpha,17beta-triol;(16.alpha.,17.beta.)-Oestra-1,3,5(10)-triene-3,16,17-triol;16.alpha.-Hydroxyestradiol;16.alpha.,17.beta.-Estriol;1,3,5-Estratriene-3beta,16alpha,17beta-triol;1,3, 5(10)-Estratriene-3,16.alpha., 17.beta.-triol;Estra-1,3,5(10)-triene-3,16,17-triol,(16R,17a)-;Estra-1,3,5(10)-trien-3, 16.alpha., 17.beta.-triol;16-alpha-Hydroxyoestradiol;16.alpha.-Estriol;16alpha-Hydroxy-17beta-estradiol;Triovex;Ovestrion;Oestra-1,3,5(10)-triene-3,16alpha,17beta-triol;3, 16.alpha.,17.beta.-Estriol;Synapause;Klimoral;Folicular hormone;16-alpha-Hydroxyestradiol;3,16.alpha., 17.beta.-Trihydroxy-1,3,5(10)-estratriene;Hemostyptanon;Estra-1,3,5(10)-triene-3,16,17-triol, (16alpha,17beta)-;Estra-1,3,5(10)-trien-3,16alpha,17beta-triol;Estriolo [Italian];Tridestrin;Estra-1,3,5(10)-trien-3,16.alpha., 17.beta.-triol;3,16-alpha,17-beta-Oestriol;3,16-alpha,17-beta-Estriol;Oestra-1,3,5(10)-triene-3,16.alpha., 17.beta.-triol;Aacifemine;16.alpha.,17.beta.-Oestriol;Deuslon-A;Oestratriol;3,16alpha,17beta-Trihydroxy-1,3,5(10)-estratriene;3,16.alpha., 17.beta.-Trihydroxy-.delta.-1,3,5-oestratriene;16.alpha.-Hydroxyoestradiol;3,16alpha,17beta-Trihydroxy-delta-1,3,5-oestratriene;A 13610;Oestriolum;Trihydroxyoestrin;Holin V;Thulol;Triodurin;Orestin;Estra-1,3,5(10)-triene-3,16.alpha.,17.beta.-triol;Oestriol [Steroidal oestrogens];Overstin;Orgastyptin;Ovestin;Estriel;(16alpha,17beta)-estra-1,3,5(10)-triene-3,16,17-triol;Theelol;Stiptanon;(16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol;
EINECS(EC#)200-022-2
Molecular FormulaC18H24O3
Molecular Weight288.38
Chemical Properties
AppearanceWhite crystalline powder
refractive index1.624
storage temp-20°C Freezer
Safety Data

Hazard T: Toxic;
Risk R60
Safety

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Other experimental reproductive effects. Mutation data reported. A steroid drug for the treatment of menopause. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes?: T (Toxic)
Risk Statements?:
? R60-61-40-45 (May impair fertility;May cause harm to the unborn child;Limited evidence of a carcinogenic effect;May cause cancer)
Safety Statements?:?
??S53-22-36/37/39-45-36/37 (Avoid exposure - obtain special instruction before use;Do not breathe dust;Wear suitable protective clothing, gloves and eye/face protection;In case of accident or if you feel unwell, seek medical advice immediately (show label where possible);Wear suitable protective clothing and gloves)
WGK Germany?: 3


Toxicity
1. ???

cyt-ham:ovr 50 μmol/L

??? TOLED5 ?? Toxicology Letters. 29 (1985),201.
2. ???

imp-gpg TDLo:20?mg/kg:ETA,TER

??? RBBIAL ?? Revista Brasileira de Biologia. 5 (1945),1.

?

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