50-35-1|thalidomideProducts Supply - Chemical intermediates Network

thalidomide cas no:50-35-1

Synonyms: 2-phthalimidoglutarimide; 2-(2,6-dioxo-3-piperidinyl)-1h-isoindole-1,3(2h)-dione

Identification

Namethalidomide
CAS50-35-1
Synonyms2-phthalimidoglutarimide; 2-(2,6-dioxo-3-piperidinyl)-1h-isoindole-1,3(2h)-dione
EINECS(EC#)200-031-1
Molecular FormulaC13H10N2O4
Molecular Weight258.23

Chemical Properties

Appearancewhite solid
refractive index1.646
storage tempStore at RT

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T:Toxic
Risk R46;R61;R21;R25;R62
Safety

Safety Information of? Thalidomide (CAS NO.50-35-1):
Hazard Codes: T
Risk Statements: 46-61-21-25-62?
R46:May cause heritable genetic damage.?
R61:May cause harm to the unborn child.?
R21:Harmful in contact with skin.?
R25 :Toxic if swallowed.?
R62:Risk of impaired fertility.
Safety Statements: 53-22-26-36/37/39-45
S53:Avoid exposure - obtain special instructions before use.?
S22:Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TI4375000
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion. Moderately toxic by skin contact and intraperitoneal routes. Human teratogenic effects by ingestion: developmental abnormalities of the musculoskeletal and cardiovascular systems. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic and teratogenic data. Human mutation data reported. It was commonly used as a prescription drug in Europe in the late 1950s and early 1960s. Its use was discontinued because it was discovered to cause serious congenital abnormalities in the fetus, notably amelia and phocomelia (absence or deformity of the limbs, including hands and feet) when taken by a woman during early pregnancy. When heated to decomposition it emits toxic fumes of NO_x. Used as a sedative and hypnotic.

Toxicity

1.	???	cyt-hmn:lym 1?mg/L	???	AMSVAZ ?? Acta Medica Scandinavica. 177 (1965),783.
2.	???	dns-rat-ipr 80?mg/kg	???	JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 171 (1970),109.
3.	???	orl-rat LD50:113?mg/kg	???	TXAPA9 ?? Toxicology and Applied Pharmacology. 14 (1969),515.
4.	???	skn-rat LD50:1550?mg/kg	???	TXAPA9 ?? Toxicology and Applied Pharmacology. 14 (1969),515.
5.	???	orl-mus LD50:2000?mg/kg	???	LIFSAK ?? Life Sciences. 3 (1964),721.
6.	???	ipr-mus LDLo:800?mg/kg	???	TXAPA9 ?? Toxicology and Applied Pharmacology. 23 (1972),288.

supplier list

Beijing Merson pharmaceutical Co., Ltd.: Tel:; Address: 2nd Floor, No.2 Building, No.14 Houshayu Duan, Jingmi Road ,Shunyi District ,Beijing 101318, P.R.China

SHILPA MEDICARE LIMITED,: Tel:+0091-8532-235006, 236328; Address: 10/80, RAJENDRA GUNJ,RAICHUR - 584 102 (INDIA)

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Yingxuan Chempharm Co., Ltd.: Tel:+86-(21)-50323911; Address: Rm.1705, No.51, JinZang Rd., Pudong, Shanghai 201206,

Molekula Limited: Tel:+44-(1747)-831066; Address: Brickfields Business Park, Gillingham, Dorset SP8 4PX,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Goly Chemical Co., Ltd.: Tel:+86-(632)-6163187; Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102,

Changzhou Institute of Materia Medica: Tel:+86-(519)-8881-0897; Address: No.300,Yanling Middle Road, Changzhou, Jiangsu 213003,

Changzhou Kangzheng Pharmachem Technology Co., Ltd.: Tel:+86-(519)-85109938; Address: No. 457, Chuangxin (North) Area, Science & Technology Park, Xinbei District, Changzhou, Jiangsu 213022,

Beijing Merson Pharmaceutical Co., Ltd: Tel:0086-10-80484934 0086-10-80484574/80483447; Address: 2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China

Daxinganling International Import&Export Co.,Ltd: Tel:86-452-6197139; Address: 5F,C Linandalijiang,Building No.25 ,9xinjiang Road ,Jianhua District

lotuschem: Tel:852-29738324; Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong

NEW FORTUNE INDUSTRIAL CO.,LTD.: Tel:+86-25-86901272/86901271; Address: C4-105 GREEN ISLAND FLOWER TOWN

Nacalai Tesque, Inc.: Tel:81 75 251 1723 81-75-251-1730; Address: Nijo Karasuma, Nakagyo-ku Kyoto 604-0855 Japan

SST: Tel:(973) 473 4300; Address: United States

thalidomide cas no:50-35-1

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