QUINIDINE SULFATE (2:1) (salt) cas no:50-54-4
Synonyms: Quinidine bisulfate;Quinidine, sulfate (2:1) (salt);Quinitex;Cinchonan-9-ol,6'-methoxy-,(9S)-,sulfate (2:1) (salt);Auriquin;Quinidex;Quinidine sulfate anhydrous;Cin-Quin;Vanquin;Quinidate;QUINIDINE;Kinichron;(S)-[(4S,5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Cinchonan-9-ol, 6-methoxy-, (9S)-, sulfate (2:1) (salt);Quinidine monosulfate;Quinidine sulfate (salt);Cin quin;Quinora;Chinidine sulfate;Quinicardine;Quinidine sulfate;SK-Quinidine sulfate;Systodin;(9S)-6′-METHOXYCINCHONAN-9-OL SULFATE (2:1) (SALT);QUINIDINE SULPHATE;CINCHONAN-9-OL, 6′-METHOXY-, (9S)-, SULFATE (2:1) (SALT) (9CI);
NameQUINIDINE SULFATE (2:1) (salt)
CAS50-54-4
SynonymsQuinidine bisulfate;Quinidine, sulfate (2:1) (salt);Quinitex;Cinchonan-9-ol,6'-methoxy-,(9S)-,sulfate (2:1) (salt);Auriquin;Quinidex;Quinidine sulfate anhydrous;Cin-Quin;Vanquin;Quinidate;QUINIDINE;Kinichron;(S)-[(4S,5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Cinchonan-9-ol, 6-methoxy-, (9S)-, sulfate (2:1) (salt);Quinidine monosulfate;Quinidine sulfate (salt);Cin quin;Quinora;Chinidine sulfate;Quinicardine;Quinidine sulfate;SK-Quinidine sulfate;Systodin;(9S)-6′-METHOXYCINCHONAN-9-OL SULFATE (2:1) (SALT);QUINIDINE SULPHATE;CINCHONAN-9-OL, 6′-METHOXY-, (9S)-, SULFATE (2:1) (SALT) (9CI);
EINECS(EC#)200-046-3
Molecular FormulaC40H48N4O4 . H2O4S
Molecular Weight747.00
Risk 22
Safety
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Safety Information of Quinidinesulfate(2:1)(salt) (50-54-4):
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 22-45
22: Do not breathe dust
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: 1544
| 1. |
|
orl-man TDLo:240 mg/kg/2W-I:EYE
|
|
JTCTDW Journal of Toxicology, Clinical Toxicology. 20 (1983),367. |
| 2. |
|
orl-wmn TDLo:272 mg/kg/17D-I:CVS
|
|
AIMDAP Archives of Internal Medicine. 145 (1985),2051. |
| 3. |
|
orl-man TDLo:40 mg/kg/2W-I:CVS
|
|
AIMDAP Archives of Internal Medicine. 145 (1985),2051. |
| 4. |
|
orl-hmn TDLo:9600 mg/kg/8W:CNS,PUL
|
|
JAMAAP JAMA, Journal of the American Medical Association. 238 (1977),884. |
| 5. |
|
orl-wmn TDLo:409 g/kg/14Y:CNS
|
|
JAMAAP JAMA, Journal of the American Medical Association. 237 (1977),2093. |
| 6. |
|
orl-man TDLo:88 mg/kg/10D-I:SYS
|
|
GASTAB Gastroenterology. 70 (1976),1136. |
| 7. |
|
orl-wmn TDLo:32 mg/kg/2D:SKN
|
|
DICPBB Drug Intelligence and Clinical Pharmacy. 16 (1982),615. |
| 8. |
|
mul-man LDLo:30 mg/kg/2D-I:CVS,PUL
|
|
AIMEAS Annals of Internal Medicine. 16 (1942),571. |
| 9. |
|
orl-rat LD50:456 mg/kg
|
|
ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),1127. |
| 10. |
|
ipr-rat LDLo:140 mg/kg
|
|
TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),156. |
