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Thymidine cas no:50-89-5

Synonyms: 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione;5-Methyl-2'-deoxyuridine;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-;2'-Deoxythymidine;5-Methyldeoxyurindine;Uridine, 2'-deoxy-5-methyl-beta-D-Ribofuranoside, thymine-1 2-deoxy-;dT;UNII-VC2W18DGKR;Thyminedeoxyriboside;Thymine-2-deoxyriboside;

Identification
NameThymidine
CAS50-89-5
Synonyms1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione;5-Methyl-2'-deoxyuridine;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-;2'-Deoxythymidine;5-Methyldeoxyurindine;Uridine, 2'-deoxy-5-methyl-beta-D-Ribofuranoside, thymine-1 2-deoxy-;dT;UNII-VC2W18DGKR;Thyminedeoxyriboside;Thymine-2-deoxyriboside;
EINECS(EC#)200-070-4
Molecular FormulaC10H14N2O5
Molecular Weight242.23
Chemical Properties
Appearancewhite crystalline powder
alpha18.6 o (C=3, H2O)
refractive index33 ° (C=1, 1mol/L NaOH)
storage temp0-6°C
Safety Data

Hazard Xi: Irritant;
Risk R20/21/22
Safety

Safty information about?Thymidine (CAS NO.50-89-5) is:
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: Xi?
Risk Statements: 20/21/22-40-36/37/38?
R20/21/22:?Harmful by inhalation, in contact with skin and if swallowed??
R40:?Limited evidence of a carcinogenic effect??
R36/37/38:?Irritating to eyes, respiratory system and skin
Safety Statements? 22-24/25-37/39-26
S22:? Do not breathe dust?
S24/25: Avoid contact with skin and eyes
S37/39:?Wear suitable gloves and eye/face protection
S26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
F 10: Keep under argon.
WGK Germany: 3
RTECS: XP2071000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 2512mg/kg (2512mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 207, Pg. 504, 1978.

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