50370-12-2|5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)-Products Supply

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)- cas no:50370-12-2

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;BL-S 578;Bidocef;Cefadrox;Cefadroxil;Cefadur;Cephadroxil;Cipadur;D-Cefadroxil;Evacef;Helicef;Neucef;Oracefal;Roxil;S 578;Sumacef;Ultracef;

Identification

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)-
CAS50370-12-2
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;BL-S 578;Bidocef;Cefadrox;Cefadroxil;Cefadur;Cephadroxil;Cipadur;D-Cefadroxil;Evacef;Helicef;Neucef;Oracefal;Roxil;S 578;Sumacef;Ultracef;
EINECS(EC#)256-555-6
Molecular FormulaC₁₆H₁₇N₃O₅S
Molecular Weight363.38

Chemical Properties

refractive index1.728

Safety Data

Hazard Xn
Risk R36/37/38
Safety

Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of SO_x and NO_x.Safety information of Cefadroxil (CAS NO.50370-12-2):
Hazard Codes?? Harmful Xn
Risk Statements?
36/37/38 Irritating to eyes, respiratory system and skin
42/43 May cause sensitization by inhalation and skin contact
Safety Statements?
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing
WGK Germany? 2
RTECS? XI0337000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 2gm/kg (2000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
mouse	LD50	intraperitoneal	> 6gm/kg (6000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
mouse	LD50	intravenous	> 1500mg/kg (1500mg/kg)	?	Infection. Vol. 8(Suppl,
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
mouse	LD50	subcutaneous	> 8gm/kg (8000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
rabbit	LD50	oral	> 6gm/kg (6000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
rat	LD50	intraperitoneal	> 6gm/kg (6000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.
rat	LD50	intravenous	> 1gm/kg (1000mg/kg)	?	Infection. Vol. 8(Suppl,
rat	LD50	oral	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. -, Pg. 552, 1990.
rat	LD50	subcutaneous	> 8gm/kg (8000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 35, Pg. 2736, 1982.

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5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)- cas no:50370-12-2

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