5053-06-5|FenspirideProducts Supply - Chemical intermediates Network

Fenspiride cas no:5053-06-5

Synonyms: 1-Oxa-3,8-diazaspiro[4.5]decan-2-one,8-(2-phenylethyl)-; Respiride

Identification

NameFenspiride
CAS5053-06-5
Synonyms1-Oxa-3,8-diazaspiro[4.5]decan-2-one,8-(2-phenylethyl)-; Respiride
EINECS(EC#)225-751-3
Molecular FormulaC15H20 N2 O2
Molecular Weight0

Chemical Properties

refractive index1.591

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intraperitoneal	210mg/kg (210mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.
guinea pig	LD50	oral	260mg/kg (260mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.
mouse	LD50	intraperitoneal	230mg/kg (230mg/kg)		Chimica Therapeutica. Vol. 4, Pg. 185, 1969.
mouse	LD50	intravenous	106mg/kg (106mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE WEAKNESS	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.
mouse	LD50	oral	250mg/kg (250mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.
rat	LD50	intravenous	122mg/kg (122mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.
rat	LD50	oral	980mg/kg (980mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 193, Pg. 111, 1971.

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Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Fenspiride cas no:5053-06-5

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