Tetramisole hydrochloride cas no:5086-74-8
Synonyms: DL-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride; Tetramisole HCl; DL-Tetramisole HCl; (+-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazolemonohydrochloride; (+-)-anthelvet; 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(+-)-imidazo(; anthelvet; bayer9051; citarin; dl-6-phenyl-2,3,5,6-tetrahydroimidazole(2,1-b)thiazole-hydrochloride; dl-tetramisolehydrochloride
NameTetramisole hydrochloride
CAS5086-74-8
SynonymsDL-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride; Tetramisole HCl; DL-Tetramisole HCl; (+-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazolemonohydrochloride; (+-)-anthelvet; 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(+-)-imidazo(; anthelvet; bayer9051; citarin; dl-6-phenyl-2,3,5,6-tetrahydroimidazole(2,1-b)thiazole-hydrochloride; dl-tetramisolehydrochloride
EINECS(EC#)225-799-5
Molecular FormulaC11H12N2S?HCl
Molecular Weight240.75
Appearancewhite to pale cream crystalline powder
storage tempKeep containers tightly closed. Store in a cool, dry area away from incompatible substances.
Hazard Xi:Irritant;
Risk R22;R36/37/38
Safety
Hazard Codes: Xn,Xi .gif)
Risk Statements: 36/37/38-20/21/22
20/21/22: Tetramisole hydrochloride (5086-74-8) is harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: NJ5950000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| duck |
LD50 |
oral |
958mg/kg (958mg/kg) |
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) |
Veterinariya. Veterinary Science. Vol. 54(5), Pg. 64, 1978. |
| human |
TDLo |
oral |
2mg/kg (2mg/kg) |
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
Toxicology and Applied Pharmacology. Vol. 20, Pg. 602, 1971. |
| mouse |
LD50 |
intravenous |
22mg/kg (22mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
| mouse |
LD50 |
oral |
210mg/kg (210mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
| mouse |
LD50 |
subcutaneous |
84mg/kg (84mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
| rat |
LD50 |
intravenous |
24mg/kg (24mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
| rat |
LD50 |
oral |
480mg/kg (480mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
| rat |
LD50 |
subcutaneous |
130mg/kg (130mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Nature. Vol. 209, Pg. 1084, 1966. |
Tetramisole hydrochloride (CAS NO.5086-74-8) hasn't been listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
