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Home > products > 5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S,10S)-

5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S,10S)- cas no:50935-04-1

Synonyms: 5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S-cis)-; Antibiotic R 588A; Carminomicin I; Carminomycin I; Carubicin

Identification
Name5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S,10S)-
CAS50935-04-1
Synonyms5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S-cis)-; Antibiotic R 588A; Carminomicin I; Carminomycin I; Carubicin
Molecular FormulaC26H27 N O10
Molecular Weight513.54
Chemical Properties
refractive index1.726
Safety Data

Safety

Deadly poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1100ug/kg (1.1mg/kg)   Antibiotiki. Vol. 29, Pg. 666, 1984.
mouse LD50 intravenous 3400ug/kg (3.4mg/kg) behavioral: tremor gastrointestinal: "hypermotility, diarrhea" Antibiotiki. Vol. 28, Pg. 90, 1983.
mouse LD50 oral 7250ug/kg (7.25mg/kg) behavioral: tremor gastrointestinal: "hypermotility, diarrhea" Antibiotiki. Vol. 28, Pg. 90, 1983.
mouse LD50 subcutaneous 3800ug/kg (3.8mg/kg) behavioral: somnolence (general depressed activity) behavioral: tremor Antibiotiki. Vol. 19, Pg. 57, 1974.

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Leawell International Limited
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ZHEJIANG HOLYPHARM BIOTECH CO.,LTD
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HANGZHOU HOLYPHARM BIOTECH CO.,LTD
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KEDE CHEMICAL CO., LTD.
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Shanghai Forever Synthesis Co.,Ltd.
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Address: Nianjiabang Rd, Pudong, Shanghai

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