51-15-0|2-Pyridinealdoxime methochlorideProducts Supply

2-Pyridinealdoxime methochloride cas no:51-15-0

Synonyms: 2-hydroxyiminomethyl-1-methylpyridinium chloride; 2-PAM chloride; Pralidoxime chloride; Pyridine-2-carbaldoxime methochloride; Pyridine-2-carboxaldoxime methochloride; N-Methylpyridinium-2-carboxaldoxime chloride~2-PAM chloride~Pralidoxime chloride~Pyridine-2-aldoxime methochloride

Identification

Name2-Pyridinealdoxime methochloride
CAS51-15-0
Synonyms2-hydroxyiminomethyl-1-methylpyridinium chloride; 2-PAM chloride; Pralidoxime chloride; Pyridine-2-carbaldoxime methochloride; Pyridine-2-carboxaldoxime methochloride; N-Methylpyridinium-2-carboxaldoxime chloride~2-PAM chloride~Pralidoxime chloride~Pyridine-2-aldoxime methochloride
EINECS(EC#)200-080-9
Molecular FormulaC7H9ClN2O
Molecular Weight172.61

Chemical Properties

Appearancewhite - off-white crystalline powder
storage temp0-6°C

Safety Data

Hazard Xn:Harmful;
Risk R20/22;R36/37/38
Safety

Safety Information of 2-Hydroxyiminomethyl-1-methylpyridinium chloride (CAS NO.51-15-0):
Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-20/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36/37/38:Irritating to eyes, respiratory system and skin
R20/21:Harmful by inhalation and in contact with skin
Safety Statements: 36-37/39-26
S36:Wear suitable protective clothing
S37/39:Wear suitable gloves and eye/face protection
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany: 3
RTECS: UU4200000
Poison by intravenous, intramuscular, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by intravenous route: coma, blood pressure increase, bronchiolar constriction and cyanosis. Used as a cholinesterase reactivator. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.

Toxicity

1.	ivn-man TDLo:14 mg/kg:CNS,PUL	34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,449.
2.	ivn-hmn TDLo:15 mg/kg:CVS	AEHLAU Archives of Environmental Health. 15 (1967),599.
3.	ivn-rat LD50:96 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 16 (1970),40.
4.	ims-rat LD50:150 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 16 (1970),40.
5.	orl-mus LD50:4100 mg/kg	JPMSAE Journal of Pharmaceutical Sciences. 53 (1964),1143.
6.	ipr-mus LD50:155 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 14 (1964),5.
7.	ivn-mus LD50:90 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 14 (1964),5.
8.	ims-mus LD50:100 mg/kg	DCTODJ Drug and Chemical Toxicology. 8 (1985),431.
9.	ims-dog LD50:75 mg/kg	FAATDF Fundamental and Applied Toxicology. 4 (2, Pt 2),(1984),S106.
10.	ivn-rbt LD50:95 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 132 (1961),50.

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2-Pyridinealdoxime methochloride cas no:51-15-0

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