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norepinephrine cas no:51-41-2

Synonyms: Arterenol; Levophed; NA; NE; noradrenalin

Identification
Namenorepinephrine
CAS51-41-2
SynonymsArterenol; Levophed; NA; NE; noradrenalin
EINECS(EC#)200-096-6
Molecular FormulaC8H11NO3
Molecular Weight169.18
Chemical Properties
Appearancecrystalline
refractive index1.66
storage temp2-8°C
Sensitive Air & Light Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T+:Verytoxic;
Risk R26/27/28
Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. A sympathomimetic vasopressor. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
T+: Very toxic
C: Corrosive
F: Flammable
Risk Statements about l-Norepinephrine (51-41-2):
R11 Highly flammable.
R34 Causes burns.
R26/27/28: Very toxic by inhalation, in contact with skin and if swallowed.
Safety Statements about l-Norepinephrine (51-41-2):
S16 Keep away from sources of ignition.
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap-suds.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.


Toxicity
1. ???

dni-hmn:oth 5800?nmol/L

??? CNREA8 ?? Cancer Research. 40 (1980),1414.
2. ???

dni-mus:oth 5800?nmol/L

??? CNREA8 ?? Cancer Research. 40 (1980),1414.
3. ???

ivn-rat LD50:100?μg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 95 (1949),502.
4. ???

orl-mus LD50:20?mg/kg

??? APTOA6 ?? Acta Pharmacologica et Toxicologica. 31 (1972),49.
5. ???

ipr-mus LD50:6?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),567.
6. ???

scu-mus LD50:5?mg/kg

??? NATWAY ?? Naturwissenschaften. 56 (1969),615.
7. ???

ivn-mus LD50:550?μg/kg

??? AEPPAE ?? Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 226 (1955),493.
8. ???

ivn-rbt LDLo:250?μg/kg

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 41 (1931),365.

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