Benzeneethanamine, N,a-dimethyl-, hydrochloride (1:1),(aS)- cas no:51-57-0

Synonyms: Benzeneethanamine,N,a-dimethyl-, hydrochloride, (S)-;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aS)- (9CI); Phenethylamine, N,a-dimethyl-, hydrochloride, (S)-(+)- (8CI);(+)-2-Methylamino-2-phenylpropane hydrochloride; (+)-L-Methamphetaminehydrochloride; (+)-Methamphetamine chloride; (+)-Methamphetamine hydrochloride;(+)-Methylamphetamine hydrochloride; (+)-N,a-Dimethylphenethylamine hydrochloride;(+)-N-Methylamphetamine hydrochloride; Adipex; Amphedroxyn; D-Methamphetaminehydrochloride; Deofed; Desfedrin; Desoxo 5; Desoxyfed; Desoxyn; Desoxyne;Destim; Desyphed; Dexoval; Dextim; Doxephrin; Doxyfed; Drinalfa; Efroxine;Eufodrinal; Gerobit; Gerovit; Hiropon; Isophen; Madrine; Metamphetaminehydrochloride; Meth; Methampex; Methamphetamine hydrochloride;Methamphetaminium chloride; Methedrine; Methedrine hydrochloride;Methylamphetamine hydrochloride; Methylisomin; Methylisomyn;N-Methylamphetamine hydrochloride; NSC 169505; Norodin hydrochloride; Pervitin;Philopon; S-(+)-Methamphetamine hydrochloride; Semoxydrine; Soxysympamine;Speed; Syndrox; Tonedron; d-Deoxyephedrine hydrochloride; d-Desoxyephedrinehydrochloride; d-Methamphetamine hydrochloride; d-Methamphetaminehydrochloride; d-Methylamphetamine hydrochloride
NameBenzeneethanamine, N,a-dimethyl-, hydrochloride (1:1),(aS)-
CAS51-57-0
SynonymsBenzeneethanamine,N,a-dimethyl-, hydrochloride, (S)-;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aS)- (9CI); Phenethylamine, N,a-dimethyl-, hydrochloride, (S)-(+)- (8CI);(+)-2-Methylamino-2-phenylpropane hydrochloride; (+)-L-Methamphetaminehydrochloride; (+)-Methamphetamine chloride; (+)-Methamphetamine hydrochloride;(+)-Methylamphetamine hydrochloride; (+)-N,a-Dimethylphenethylamine hydrochloride;(+)-N-Methylamphetamine hydrochloride; Adipex; Amphedroxyn; D-Methamphetaminehydrochloride; Deofed; Desfedrin; Desoxo 5; Desoxyfed; Desoxyn; Desoxyne;Destim; Desyphed; Dexoval; Dextim; Doxephrin; Doxyfed; Drinalfa; Efroxine;Eufodrinal; Gerobit; Gerovit; Hiropon; Isophen; Madrine; Metamphetaminehydrochloride; Meth; Methampex; Methamphetamine hydrochloride;Methamphetaminium chloride; Methedrine; Methedrine hydrochloride;Methylamphetamine hydrochloride; Methylisomin; Methylisomyn;N-Methylamphetamine hydrochloride; NSC 169505; Norodin hydrochloride; Pervitin;Philopon; S-(+)-Methamphetamine hydrochloride; Semoxydrine; Soxysympamine;Speed; Syndrox; Tonedron; d-Deoxyephedrine hydrochloride; d-Desoxyephedrinehydrochloride; d-Methamphetamine hydrochloride; d-Methamphetaminehydrochloride; d-Methylamphetamine hydrochloride
EINECS(EC#)200-106-9
Molecular FormulaC10H15 N . Cl H
Molecular Weight185.72
storage tempControlled Substance, -20°C Freezer
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard T
Risk 25
Safety
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx and HCl. See also BENZEDRINE and various amphetamines.
Hazard Codes
T
Risk Statements 25
R25 :Toxic if swallowed.
Safety Statements 45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 3249
RTECS SH5455000
HazardClass 6.1(b)
PackingGroup III
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
guinea pig |
LD50 |
oral |
90mg/kg (90mg/kg) |
|
Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 351, 1954. |
mammal (species unspecified) |
LD50 |
intravenous |
9500ug/kg (9.5mg/kg) |
|
German Offenlegungsschrift Patent Document. Vol. #2901868, |
mammal (species unspecified) |
LD50 |
subcutaneous |
14mg/kg (14mg/kg) |
|
German Offenlegungsschrift Patent Document. Vol. #2901868, |
man |
TCLo |
inhalation |
28mg/kg (28mg/kg) |
BEHAVIORAL: EXCITEMENT
CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION |
Veterinary and Human Toxicology. Vol. 41, Pg. 28, 1999. |
mouse |
LD50 |
intraperitoneal |
15mg/kg (15mg/kg) |
|
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 346, 1972. |
mouse |
LD50 |
intravenous |
6300ug/kg (6.3mg/kg) |
|
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02170, |
mouse |
LD50 |
subcutaneous |
7560ug/kg (7.56mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT |
Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946. |
rat |
LD50 |
subcutaneous |
10930ug/kg (10.93mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 253, Pg. 466, 1990. |