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Benzeneethanamine, N,a-dimethyl-, hydrochloride (1:1),(aS)- cas no:51-57-0

Synonyms: Benzeneethanamine,N,a-dimethyl-, hydrochloride, (S)-;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aS)- (9CI); Phenethylamine, N,a-dimethyl-, hydrochloride, (S)-(+)- (8CI);(+)-2-Methylamino-2-phenylpropane hydrochloride; (+)-L-Methamphetaminehydrochloride; (+)-Methamphetamine chloride; (+)-Methamphetamine hydrochloride;(+)-Methylamphetamine hydrochloride; (+)-N,a-Dimethylphenethylamine hydrochloride;(+)-N-Methylamphetamine hydrochloride; Adipex; Amphedroxyn; D-Methamphetaminehydrochloride; Deofed; Desfedrin; Desoxo 5; Desoxyfed; Desoxyn; Desoxyne;Destim; Desyphed; Dexoval; Dextim; Doxephrin; Doxyfed; Drinalfa; Efroxine;Eufodrinal; Gerobit; Gerovit; Hiropon; Isophen; Madrine; Metamphetaminehydrochloride; Meth; Methampex; Methamphetamine hydrochloride;Methamphetaminium chloride; Methedrine; Methedrine hydrochloride;Methylamphetamine hydrochloride; Methylisomin; Methylisomyn;N-Methylamphetamine hydrochloride; NSC 169505; Norodin hydrochloride; Pervitin;Philopon; S-(+)-Methamphetamine hydrochloride; Semoxydrine; Soxysympamine;Speed; Syndrox; Tonedron; d-Deoxyephedrine hydrochloride; d-Desoxyephedrinehydrochloride; d-Methamphetamine hydrochloride; d-Methamphetaminehydrochloride; d-Methylamphetamine hydrochloride

Identification
NameBenzeneethanamine, N,a-dimethyl-, hydrochloride (1:1),(aS)-
CAS51-57-0
SynonymsBenzeneethanamine,N,a-dimethyl-, hydrochloride, (S)-;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aS)- (9CI); Phenethylamine, N,a-dimethyl-, hydrochloride, (S)-(+)- (8CI);(+)-2-Methylamino-2-phenylpropane hydrochloride; (+)-L-Methamphetaminehydrochloride; (+)-Methamphetamine chloride; (+)-Methamphetamine hydrochloride;(+)-Methylamphetamine hydrochloride; (+)-N,a-Dimethylphenethylamine hydrochloride;(+)-N-Methylamphetamine hydrochloride; Adipex; Amphedroxyn; D-Methamphetaminehydrochloride; Deofed; Desfedrin; Desoxo 5; Desoxyfed; Desoxyn; Desoxyne;Destim; Desyphed; Dexoval; Dextim; Doxephrin; Doxyfed; Drinalfa; Efroxine;Eufodrinal; Gerobit; Gerovit; Hiropon; Isophen; Madrine; Metamphetaminehydrochloride; Meth; Methampex; Methamphetamine hydrochloride;Methamphetaminium chloride; Methedrine; Methedrine hydrochloride;Methylamphetamine hydrochloride; Methylisomin; Methylisomyn;N-Methylamphetamine hydrochloride; NSC 169505; Norodin hydrochloride; Pervitin;Philopon; S-(+)-Methamphetamine hydrochloride; Semoxydrine; Soxysympamine;Speed; Syndrox; Tonedron; d-Deoxyephedrine hydrochloride; d-Desoxyephedrinehydrochloride; d-Methamphetamine hydrochloride; d-Methamphetaminehydrochloride; d-Methylamphetamine hydrochloride
EINECS(EC#)200-106-9
Molecular FormulaC10H15 N . Cl H
Molecular Weight185.72
Chemical Properties
storage tempControlled Substance, -20°C Freezer
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T
Risk 25
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx and HCl. See also BENZEDRINE and various amphetamines.
Hazard Codes ToxicT
Risk Statements 25
R25 :Toxic if swallowed.
Safety Statements 45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 3249
RTECS SH5455000
HazardClass 6.1(b)
PackingGroup III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 90mg/kg (90mg/kg)   Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 351, 1954.
mammal (species unspecified) LD50 intravenous 9500ug/kg (9.5mg/kg)   German Offenlegungsschrift Patent Document. Vol. #2901868,
mammal (species unspecified) LD50 subcutaneous 14mg/kg (14mg/kg)   German Offenlegungsschrift Patent Document. Vol. #2901868,
man TCLo inhalation 28mg/kg (28mg/kg) BEHAVIORAL: EXCITEMENT

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION
Veterinary and Human Toxicology. Vol. 41, Pg. 28, 1999.
mouse LD50 intraperitoneal 15mg/kg (15mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 346, 1972.
mouse LD50 intravenous 6300ug/kg (6.3mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02170,
mouse LD50 subcutaneous 7560ug/kg (7.56mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946.
rat LD50 subcutaneous 10930ug/kg (10.93mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 253, Pg. 466, 1990.

 

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