Neostigmine methyl sulfate cas no:51-60-5
Synonyms: Prostigmin methyl sulfate;Hodostin;Neostigmeth;Benzenaminium,3-[[(dimethylamino)carbonyl]- oxy]-N,N,N-trimethyl-,methyl sulfate;AR-32;Normastigmin;Carbamic acid, N,N-dimethyl-, 3-(trimethylammonio)phenyl ester, methyl sulfate;Ammonium, (m-hydroxyphenyl)trimethyl-, methyl sulfate, dimethylcarbamate;Juvastigmin;Polstigmine;Stigmanol methyl sulfate;(3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamic ester;[3-(Dimethylcarbamoyl)oxyphenyl]trimethylammonium methyl sulfate;Syntostigmin methyl sulfate;Synthostigmine methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfonatooxymethane;Vagostigmin;Philostigmin methyl sulfate;Kirkstigmine methyl sulfate;(m-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate;Benzenaminium, 3-[[ (dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfooxymethane;Syntostigmin;Syntostigmine methyl sulfate;Dimethylcarbamic ester of 3-oxyphenyltrimethylammonium methylsulfato;Leostigmine methyl sulfate;Synstigmine;Proserine methyl sulfate;Proserine;Neostigmine monomethyl sulfate;Carbamic acid, dimethyl-, ester with (m-hydroxyphenyl)trimethylammonium methyl sulfate;[3-(Dimethylcarbamoxy)phenyl]trimethylammonium methyl sulfate;Neostigmine methosulfate;Vagostigmine methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium;Syntostigmin (injection);Prostigmin;SB-23;Neoeserine methyl sulfate;Prostigmine methyl sulfate;Kirkstigmine;Proserin;Ammonium, [3-(dimethylcarbamoyloxy)phenyl]trimethyl-, methyl sulfate;Stigmosan methyl sulfate;Eustigmin methyl sulfate;Neostigmine methylsulfates;TL-1394;Neostigmine methylsulfate (JP14/USP);Prostigmin (TN);Neostigmine Methylsulfate USP29/EP5;Nefazodone;neostigmine metilsulfate;
NameNeostigmine methyl sulfate
CAS51-60-5
SynonymsProstigmin methyl sulfate;Hodostin;Neostigmeth;Benzenaminium,3-[[(dimethylamino)carbonyl]- oxy]-N,N,N-trimethyl-,methyl sulfate;AR-32;Normastigmin;Carbamic acid, N,N-dimethyl-, 3-(trimethylammonio)phenyl ester, methyl sulfate;Ammonium, (m-hydroxyphenyl)trimethyl-, methyl sulfate, dimethylcarbamate;Juvastigmin;Polstigmine;Stigmanol methyl sulfate;(3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamic ester;[3-(Dimethylcarbamoyl)oxyphenyl]trimethylammonium methyl sulfate;Syntostigmin methyl sulfate;Synthostigmine methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfonatooxymethane;Vagostigmin;Philostigmin methyl sulfate;Kirkstigmine methyl sulfate;(m-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate;Benzenaminium, 3-[[ (dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfooxymethane;Syntostigmin;Syntostigmine methyl sulfate;Dimethylcarbamic ester of 3-oxyphenyltrimethylammonium methylsulfato;Leostigmine methyl sulfate;Synstigmine;Proserine methyl sulfate;Proserine;Neostigmine monomethyl sulfate;Carbamic acid, dimethyl-, ester with (m-hydroxyphenyl)trimethylammonium methyl sulfate;[3-(Dimethylcarbamoxy)phenyl]trimethylammonium methyl sulfate;Neostigmine methosulfate;Vagostigmine methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium;Syntostigmin (injection);Prostigmin;SB-23;Neoeserine methyl sulfate;Prostigmine methyl sulfate;Kirkstigmine;Proserin;Ammonium, [3-(dimethylcarbamoyloxy)phenyl]trimethyl-, methyl sulfate;Stigmosan methyl sulfate;Eustigmin methyl sulfate;Neostigmine methylsulfates;TL-1394;Neostigmine methylsulfate (JP14/USP);Prostigmin (TN);Neostigmine Methylsulfate USP29/EP5;Nefazodone;neostigmine metilsulfate;
EINECS(EC#)200-109-5
Molecular FormulaC13H22N2O6S
Molecular Weight334.43
AppearanceCrystalline Solid
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard T+: Very toxic;
Risk R26/27/28;R36/37/38;R42/43
Safety
A deadly poison by ingestion, intravenous, subcutaneous, intraperitoneal, and intramuscular routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of SOx, NH3, and NOx. See also Carbamates.
Hazard Codes: 
T+
Risk Statements: 28-36/37/38-42/43-26/27/28
R36/37/38:Irritating to eyes, respiratory system and skin ;
R42/43:May cause sensitization by inhalation and skin contact ;
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed ;
Safety Statements: 36-45-36/37/39-28
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) ;
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection ;
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer);
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: CY1225000
HazardClass: 6.1(a)
PackingGroup: II
| 1. |
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scu-rat LD50:334 µg/kg
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TXAPA9 Toxicology and Applied Pharmacology. 25 (1973),569. |
| 2. |
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orl-mus LD50:7500 µg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),16. |
| 3. |
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ipr-mus LD50:230 µg/kg
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ATXKA8 Archiv fuer Toxikologie. 29 (1972),39. |
| 4. |
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scu-mus LD50:420 µg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),16. |
| 5. |
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ivn-mus LD50:160 µg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),16. |
| 6. |
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scu-dog LD50:50 µg/kg
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NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB158-508 . |
| 7. |
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scu-cat LDLo:50 µg/kg
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NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB158-508 . |
| 8. |
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ims-rbt LD50:310 µg/kg
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 81 (1950),276. |
