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Dextroamphetamine sulfate [USAN] cas no:51-63-8

Synonyms: D-AMPHETAMINE SULFATE;(+)-alpha-methylphenethylaminesulfate(2:1);(+)-amitrene;(+)-amphetaminesulfate;acedron;adjudets;adrizine;afatin

Identification
NameDextroamphetamine sulfate [USAN]
CAS51-63-8
SynonymsD-AMPHETAMINE SULFATE;(+)-alpha-methylphenethylaminesulfate(2:1);(+)-amitrene;(+)-amphetaminesulfate;acedron;adjudets;adrizine;afatin
EINECS(EC#)200-111-6
Molecular FormulaC18H26N2 . H2O4S
Molecular Weight368.49092
Chemical Properties
Appearancewhite powder
storage tempDesiccate at RT
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T
Risk 25
Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. A human teratogen that causes developmental abnormalities of the central nervous system. Experimental reproductive effects including other teratogenic effects. A habit-forming stimulant. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also other benzidrine compounds and SULFATES.
Hazard Codes:
T: Toxic
Risk Statements about d-Benzedrine sulfate (CAS No.:51-63-8):
R25 Toxic if swallowed.
Safety Statements about d-Benzedrine sulfate (CAS No.:51-63-8):
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)


Toxicity
1.    

orl-rat LD50:32 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research, 33 (1983),1411.
2.    

ipr-rat LD50:43,200 µg/kg

    TXAPA9    Toxicology and Applied Pharmacology, 29 (1974),397.
3.    

ivn-rat LD50:30 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics, 110 (1954),180.
4.    

orl-mus LD50:10 mg/kg

    JMCMAR    Journal of Medicinal Chemistry, 18 (1975),71.
5.    

ipr-mus LD50:9700 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics, 135 (1962),240.
6.    

scu-mus LD50:16 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie, 184 (1970),34.
7.    

ivn-mus LD50:30 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics, 137 (1962),365.
8.    

orl-dog LD50:10 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine, 118 (1965),557.
9.    

ivn-dog LD50:3 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine, 118 (1965),557.
10.    

ivn-rbt LD50:10 mg/kg

    JPETAB    Journal o

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