51-74-1|Histamine phosphateProducts Supply - Chemical intermediates Network

Histamine phosphate cas no:51-74-1

Synonyms: Histamine acid phosphate;1H-Imidazole-4-ethanamine,compounds,phosphate (1:2);Histamine Diphosphate;Histamine bisphosphate monohydrate;

Identification

NameHistamine phosphate
CAS51-74-1
SynonymsHistamine acid phosphate;1H-Imidazole-4-ethanamine,compounds,phosphate (1:2);Histamine Diphosphate;Histamine bisphosphate monohydrate;
EINECS(EC#)200-118-4
Molecular FormulaC₅H₉N₃^.2(H₃PO₄)
Molecular Weight307.13

Chemical Properties

AppearanceWhite crystal powder
storage temp−20°C

Safety Data

Hazard Xn:;
Risk 20/21/22-36/37/38-42/43-41-37/38-22
Safety

A deadly poison by intravenous and parenteral routes. Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NO_x and PO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intravenous	608ug/kg (0.608mg/kg)	LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION	Journal of Pharmaceutical Sciences. Vol. 57, Pg. 1543, 1968.
guinea pig	LDLo	parenteral	746ug/kg (0.746mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1574, 1970.
mouse	LD50	intraperitoneal	913mg/kg (913mg/kg)		Journal of Pharmaceutical Sciences. Vol. 59, Pg. 1659, 1970.
mouse	LD50	intravenous	333mg/kg (333mg/kg)		Proceedings of the Society for Experimental Biology and Medicine. Vol. 90, Pg. 726, 1955.
mouse	LD50	oral	807mg/kg (807mg/kg)		Proceedings of the Society for Experimental Biology and Medicine. Vol. 122, Pg. 685, 1966.
rabbit	LD50	intravenous	2763ug/kg (2.763mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 299, 1942.
rabbit	LDLo	parenteral	1mg/kg (1mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925.
rat	LD50	intraperitoneal	1781mg/kg (1781mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 119, Pg. 444, 1957.
rat	LDLo	intravenous	900mg/kg (900mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925.

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Histamine phosphate cas no:51-74-1

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