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19-Norpregn-4-en-20-yn-3-one,17-(acetyloxy)-, (17a)- cas no:51-98-9

Synonyms: 19-Nor-17a-pregn-4-en-20-yn-3-one,17-hydroxy-, acetate (6CI,8CI);17-Acetoxy-19-nor-17a-pregn-4-en-20-yn-3-one;17a-Ethinyl-19-nortestosteroneacetate;17a-Ethinyl-4-estrene-17b-ol-acetate-3-one;17b-Acetoxy-17a-ethinyl-4-estren-3-one;17b-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one acetate;19-Norethynyltestosterone acetate;Aygestin;Estalis;Gynovlane;Milli-Anovlar;Milligynon;Miniphase;NSC 22844;Norethindrone 17-acetate;Norethindrone acetate;Norethynyltestosteroneacetate;Norlutate;Norlutin acetate;Orlutate;Primolut-Nor;

Identification
Name19-Norpregn-4-en-20-yn-3-one,17-(acetyloxy)-, (17a)-
CAS51-98-9
Synonyms19-Nor-17a-pregn-4-en-20-yn-3-one,17-hydroxy-, acetate (6CI,8CI);17-Acetoxy-19-nor-17a-pregn-4-en-20-yn-3-one;17a-Ethinyl-19-nortestosteroneacetate;17a-Ethinyl-4-estrene-17b-ol-acetate-3-one;17b-Acetoxy-17a-ethinyl-4-estren-3-one;17b-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one acetate;19-Norethynyltestosterone acetate;Aygestin;Estalis;Gynovlane;Milli-Anovlar;Milligynon;Miniphase;NSC 22844;Norethindrone 17-acetate;Norethindrone acetate;Norethynyltestosteroneacetate;Norlutate;Norlutin acetate;Orlutate;Primolut-Nor;
EINECS(EC#)200-132-0
Molecular FormulaC22H28O3
Molecular Weight340.46
Chemical Properties
refractive index-34 ° (C=1, Dioxane)
Safety Data

Hazard Xn:Harmful
Risk R40;R48
Safety

Suspected carcinogen with experimental tumorigenic data. Human reproductive effects by ingestion and implant routes: menstrual cycle changes, postpartum effects, and changes in fertility. A human teratogen by an unspecified route with developmental abnormalities of the urogenital system. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used in the treatment of menstrual disorders and uterine bleeding.
Safety Information about [(8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate (51-98-9):
Hazard Codes:?
Xn:?
Risk Statements bout [(8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate (51-98-9):?
R40: ited evidence of a carcinogenic effect.
R48: Danger of serious damage to health by prolonged exposure.
Safety Statements bout [(8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate (51-98-9):?
S36/37: Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS: RC8965000


Toxicity
1. ???

dlt-mus-orl 1120?mg/kg/4W

??? MUREAV ?? Mutation Research. 26 (1974),535.
2. ???

spm-mus-orl 1120?mg/kg/4W

??? MUREAV ?? Mutation Research. 26 (1974),535.
3. ???

orl-wmn TDLo:2190?μg/kg (52W pre):REP

??? BMJOAE ?? British Medical Journal. 2 (1969),730.
4. ???

unr-wmn TDLo:15?mg/kg (female 13-30W post):TER

??? OBGNAS ?? Obstetrics and Gynecology. 22 (1963),210.

supplier list

Chem-Base (Nantong) Laboratories Co.,Ltd.
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Address: Room 403, Hauli Bldg, 6 Gongnong Road, Nantong, China
Luna Chemicals Co.,Ltd.
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Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China
Zhejiang Medicines & Health Products Import & Exp...
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Ancheng Pharma Limited
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Biosyn Healthy Pharma Co.,Ltd.
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Address: Factory Address锛欸olden Industrial District, Shanggao Town, Jiangxi Province Sales Department锛?RM 406, 12 Keyan Rd. West, Nankai District, Tianjin, China
Sunji & Co., Ltd.
Tel:86-755-8825 1355 /1365 /1379
Address: Room 2103-2104, Block C , Huangdu Plaza, 3008 Yitian Road, Shenzhen 518048, P.R. of China
Sunasia Co., Ltd.
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Zhejiang Xianju Junye Pharmaceutical Co., Ltd.
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Address: Hebu Bridge,Xianju,Zhejiang,China
N-Techem International Co.Ltd.
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Zhejiang Shenzhou Pharmaceutical Co., Ltd.
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Address: No. 14 Chuanchengnan Road Chengguan Town Xianju County, Zhejiang, China
SINOCO CHEMICAL CO., LIMITED
Tel:+86-571-81956191, 81956192
Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.
Pfizer
Tel:+44-(304)-616161
Address: Walton Oaks, Dorking Road, Tadworth, Surrey KT20 7NS,
Pfizer Inc.
Tel:+1-(269)-833-5844
Address: 7000 Portage Road, Kalamazoo, Michigan 49001,
Hunan Steroid Chemicals Co., Ltd.
Tel:0086 731 2762868
Address: Xin Wei Ming Zuo Bldg., No. 460, Shaoshan Rd, Changsha, Hunan 410007,
Emerald-Shanghai Incorporation
Tel:+86-(21)-6864-0170
Address: Dong Fang Road 2851 Lane 22-1202, Shanghai,

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