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2-Pyrrolidinone,methyl- cas no:51013-18-4

Synonyms: Methylpyrrolidone

Identification
Name2-Pyrrolidinone,methyl-
CAS51013-18-4
SynonymsMethylpyrrolidone
Molecular FormulaC5H9 N O
Molecular Weight99.15
Safety Data

Safety

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 4400mg/kg (4400mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(6), Pg. 84, 1970.
mouse LD50 intraperitoneal 2310mg/kg (2310mg/kg)   Yokohama Igaku. Yokohama Medicine. Vol. 31, Pg. 327, 1980.
mouse LDLo oral 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: OTHER CHANGES

BLOOD: CHANGES IN SPLEEN
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 27, 1965.
rabbit LD50 oral 3500mg/kg (3500mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(6), Pg. 84, 1970.
rat LDLo oral 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: FATTY LIVER DEGERATION

BLOOD: CHANGES IN SPLEEN
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 27, 1965.

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