51333-22-3|S-budesonideProducts Supply - Chemical intermediates Network

S-budesonide cas no:51333-22-3

Synonyms: Budesonide

Identification

NameS-budesonide
CAS51333-22-3
SynonymsBudesonide
EINECS(EC#)257-139-7
Molecular FormulaC25H34O6
Molecular Weight430.54

Chemical Properties

Appearancewhite solid
refractive index1.592
storage tempStore at RT

Safety Data

Hazard Xn:Harmful
Risk R40
Safety

Hazard Codes:? Harmful Xn
Risk Statements: 40-36/37/38-20/21/22?
R40: Limited evidence of a carcinogenic effect.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 22-36-26?
S22: Do not breathe dust.?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: TU3723000
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes.

HS Code 29372900

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	subcutaneous	173mg/kg (173mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
man	TCLo	inhalation	34ug/kg (0.034mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"	Australian and New Zealand Journal of Medicine. Vol. 22, Pg. 511, 1992.
mouse	LD50	intraperitoneal	179mg/kg (179mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse	LD50	intravenous	124mg/kg (124mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse	LD50	oral	4750mg/kg (4750mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse	LD50	subcutaneous	53600ug/kg (53.6mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat	LD50	intraperitoneal	138mg/kg (138mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat	LD50	intravenous	98900ug/kg (98.9mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat	LD50	oral	> 3200mg/kg (3200mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat	LD50	subcutaneous	58400ug/kg (58.4mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.

supplier list

INFA S.P.A.: Tel:+39-02-777281; Address: Via Salvini 10, 20122 Milan (Italy)

SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Changzhou Leo Chemical Co.,Ltd.: Tel:; Address: NO. 538 XINQING ROAD, XINZHA TOWN, ZHONGLOU DISTRICT, CHANGZHOU, JIANGSU, CHINA

Varda Biotech Pvt. Ltd.: Tel:+91-(22)-6693 5686; Address: #110 & 111 Kartik Complex, New Link Road, Andheri (W), Mumbai, Maharashtra 400 053,

Hubei Zhengdao Biochem Co., Ltd.: Tel:+86-(27)-61257867; Address:

SNC International Co., Ltd.: Tel:+86-(22)-2822-1962; Address: Room No. 711, Minmetals Building, No. 47, Xiangjiang Road, Hexi District, Tianjin 300210,

Taifa Pharma: Tel:+86-(571)-8511-4466, 8511-4477, 8521-5531; Address: No.14, Industrial East Road, Xianju, Zhejiang 317300,

Tianjin Hi-Tesion Bio&Chem Co., Ltd.: Tel:+86-(22)-2372-5099; Address: C1506, Wanhao Mansion, No.333 Binshuixi Road, Nankai District, Tianjin 300381,

Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Nanjing Samwon International Limited: Tel:+86-(25)-84873444; Address: 1108, BLDG B, New Century Plaza, No 1, South Taiping Rd., Nanjing, Jiangsu 210002,

Shreeji Pharma International: Tel:+91-265-3019110; Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018,

Beijing Hengrun Weiyuan Biotechnologies,. Inc.: Tel:+86-(10)-6969-6397; Address: Room A624, No.58 Liangguan Road, Fangshan District, Beijing 102000,

shandong taihua bio.&teh co.,ltd: Tel:+86-538-3092058; Address: 399 st.peitianmen,taian high-tech,taian shandong province,china

Tianjin Pacific Chemical & Pharmaceutical Co., Ltd. (TPCPC): Tel:86-22-88518581; Address: No.27, Baoyuan Road, Jinnan District Industrial Park, Tianjin City, China

Shanghai Hope Chem Co., Ltd.: Tel:86-21-61723543; Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H

S-budesonide cas no:51333-22-3

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