51762-05-1|5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methoxy-8-oxo-,(6R,7R)-Products Supply

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methoxy-8-oxo-,(6R,7R)- cas no:51762-05-1

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methoxy-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methoxy-8-oxo-, (6R,7R)-(9CI); CGP 9000; Cefroxadine; Oraspor

Identification

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methoxy-8-oxo-,(6R,7R)-
CAS51762-05-1
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methoxy-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methoxy-8-oxo-, (6R,7R)-(9CI); CGP 9000; Cefroxadine; Oraspor
EINECS(EC#)257-391-8
Molecular FormulaC16H19 N3 O5 S
Molecular Weight365.44

Chemical Properties

refractive index1.678

Safety Data

Safety

Mildly toxic by ingestion and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 1gm/kg (1000mg/kg)	?	Drugs in Japan Vol. -, Pg. 689, 1995.
mouse	LD50	intraperitoneal	7090mg/kg (7090mg/kg)	?	Journal of Antibiotics. Vol. 29, Pg. 653, 1976.
mouse	LD50	oral	> 13500mg/kg (13500mg/kg)	behavioral: somnolence (general depressed activity) gastrointestinal: "hypermotility, diarrhea"	Chemotherapy Vol. 28(Suppl,
mouse	LD50	subcutaneous	13500mg/kg (13500mg/kg)	behavioral: somnolence (general depressed activity) gastrointestinal: "hypermotility, diarrhea"	Chemotherapy Vol. 28(Suppl,
rabbit	LD50	intraperitoneal	> 4gm/kg (4000mg/kg)	kidney, ureter, and bladder: structural or functional changes in ureter kidney, ureter, and bladder: other changes	Chemotherapy Vol. 28(Suppl,
rabbit	LD50	oral	10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. APP-11, 1982.
rat	LD50	intraperitoneal	6gm/kg (6000mg/kg)	behavioral: ataxia gastrointestinal: "hypermotility, diarrhea" skin and appendages (skin): hair: other	Chemotherapy Vol. 28(Suppl,
rat	LD50	oral	> 22500mg/kg (22500mg/kg)	behavioral: altered sleep time (including change in righting reflex) behavioral: somnolence (general depressed activity) gastrointestinal: "hypermotility, diarrhea"	Chemotherapy Vol. 28(Suppl,
rat	LD50	subcutaneous	> 15gm/kg (15000mg/kg)	sense organs and special senses: mydriasis (pupillary dilation): eye behavioral: altered sleep time (including change in righting reflex) skin and appendages (skin): hair: other	Chemotherapy Vol. 28(Suppl,

supplier list

Sinotau International Co. Ltd.: Tel:+86-(10)-84926864; Address: 4th Area No. 5 Courtyard Anwaibeiyuan, Chaoyang District, Beijing 100012,

Leawell International Limited: Tel:+852-(2576)-0298; Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Beijing SinoTau Intl. Co., Ltd: Tel:0086-10-84926864 / 84927339; Address: Room 309 KeYanLou 4th Area No. 5 Courtyard Anwaibeiyuan Chaoyang District Beijing 100012

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methoxy-8-oxo-,(6R,7R)- cas no:51762-05-1

Directory

supplier list