51773-92-3|4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,hydrochloride (1:1), (aS)-rel-Products Supply

4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,hydrochloride (1:1), (aS)-rel- cas no:51773-92-3

Synonyms: 4-Quinolinemethanol,a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (aS)-rel- (9CI);4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (R*,S*)-(?à)-;4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-, monohydrochloride, (R*,S*)-;Loriam;Mefloquin hydrochloride;NSC 157387;Ro21-5998/001;

Identification

Name4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,hydrochloride (1:1), (aS)-rel-
CAS51773-92-3
Synonyms4-Quinolinemethanol,a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (aS)-rel- (9CI);4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (R*,S*)-(?à)-;4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-, monohydrochloride, (R*,S*)-;Loriam;Mefloquin hydrochloride;NSC 157387;Ro21-5998/001;
EINECS(EC#)257-412-0
Molecular FormulaC₁₇H₁₆F₆N₂O^.HCl
Molecular Weight414.77

Chemical Properties

AppearanceOff-white to yellow solid.
storage tempStore only in the original container. Keep container tightly sealed.

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Hazard Codes of Mefloquine hydrochloride (CAS NO.51773-92-3): Harmful Xn
Risk Statements: 22
R22: Harmful if swallowed.
WGK Germany: 3
RTECS: VC0308000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	11mg/kg/2W-I (11mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Annals of Internal Medicine. Vol. 114, Pg. 994, 1991.
man	TDLo	oral	18mg/kg/5W-I (18mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS BEHAVIORAL: GENERAL ANESTHETIC	Annals of Internal Medicine. Vol. 117, Pg. 1058, 1992.
man	TDLo	oral	96mg/kg/52D-I (96mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT BEHAVIORAL: AGGRESSION	Archives of Internal Medicine. Vol. 154, Pg. 2360, 1994.
rat	LD50	intraperitoneal	130mg/kg (130mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Acta Tropica. Vol. 37, Pg. 232, 1980.
rat	LD50	oral	880mg/kg (880mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Acta Tropica. Vol. 37, Pg. 232, 1980.
women	TDLo	oral	15mg/kg/3W-I (15mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA	Medical Journal of Australia. Vol. 161, Pg. 453, 1994.

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SourcingChem From China: Tel:13385832632; Address: No.1560 South Lake District,

suchem pharma co.,limited: Tel:86-57781172668; Address: wenzhou, China

4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,hydrochloride (1:1), (aS)-rel- cas no:51773-92-3

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