518-75-2|3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)-Products Supply

3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)- cas no:518-75-2

Synonyms: 3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-; Citrinin(6CI); (-)-Citrinin;4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid;NSC 186

Identification

Name3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)-
CAS518-75-2
Synonyms3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-; Citrinin(6CI); (-)-Citrinin;4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid;NSC 186
EINECS(EC#)208-257-2
Molecular FormulaC13H14 O5
Molecular Weight250.27

Chemical Properties

refractive index1.595
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(a)

Safety Data

Hazard T
Risk 23/24/25-40-36/37/38
Safety

Poison by ingestion and other routes. An experimental teratogen. Other experimental reproductive effects. A severe skin irritant. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information of Citrinin (CAS NO.518-75-2):
Hazard Codes: T
Risk Statements: 23/24/25-40-36/37/38
23: Toxic by inhalation
24: Toxic in contact with skin
25: Toxic if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
40: Limited evidence of a carcinogenic effect
Safety Statements: 26-36/37/39-45-22-7/9
7: Keep container tightly closed
9: Keep container in a well-ventilated place
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	subcutaneous	37mg/kg (37mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 173, 1946.
hamster	LD50	intraperitoneal	66mg/kg (66mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 355, 1978.
hamster	LD50	oral	75mg/kg (75mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 355, 1978.
mouse	LD50	intraperitoneal	35mg/kg (35mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 173, 1946.
mouse	LD50	oral	112mg/kg (112mg/kg)		Toxicology and Applied Pharmacology. Vol. 37, Pg. 139, 1976.
mouse	LD50	subcutaneous	73mg/kg (73mg/kg)		Food and Cosmetics Toxicology. Vol. 15, Pg. 29, 1977.
rabbit	LD50	intraperitoneal	50mg/kg (50mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	Food and Chemical Toxicology. Vol. 21, Pg. 487, 1983.
rabbit	LD50	intravenous	19mg/kg (19mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 173, 1946.
rabbit	LD50	oral	134mg/kg (134mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	Food and Chemical Toxicology. Vol. 21, Pg. 487, 1983.
rat	LD50	intraperitoneal	50mg/kg (50mg/kg)		Pharmaceutical Bulletin. Vol. 3, Pg. 337, 1955.
rat	LD50	subcutaneous	67mg/kg (67mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 173, 1946.

supplier list

Beijing Rapidbio Science Co. Ltd: Tel:86-10-63395349; Address: D0103,Wangfengjiye Building,Fengtai District, Beijing, China

Kainic.com: Tel:1- (858) 452-9925; Address: United States

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

Finetech Industry limited.: Tel:86-27-87465837; Address: chukang Road, Wuhan, Hubei 430073,

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road, Shirley, NY 11967, USA

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

pribolab: Tel:+86-13311089404; Address: Lizeyayuan No10,10floor,lize road,fengtai Area,bejing.

Suzhou Industrial Park Yacoo Chemical Reagent Co., Ltd.: Tel:86-512-62956016; Address: Suite 209 A3 Building 218, Xinghu Rd, Suzhou Industrial Park, SuZhou, Jiangsu 215125,

CFM Oskar Tropitzsch: Tel:+49-(9231)-9619-0; Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

TELELIN PHARM CHEMICAL CO.,LTD: Tel:86-311-83953206; Address: pingandajie

3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)- cas no:518-75-2

Directory

supplier list