Matrine cas no:519-02-8
Synonyms: Matridin-15-one;Matridin-15-one (9CI);1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]- naphthyridin-10-one,dodecahydro-,(7aS,- 13aR,13bR,13cS)-;Matrene, (+)-;5-24-02-00301 (Beilstein Handbook Reference);(+)-Matrine;
NameMatrine
CAS519-02-8
SynonymsMatridin-15-one;Matridin-15-one (9CI);1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]- naphthyridin-10-one,dodecahydro-,(7aS,- 13aR,13bR,13cS)-;Matrene, (+)-;5-24-02-00301 (Beilstein Handbook Reference);(+)-Matrine;
EINECS(EC#)209-012-2
Molecular FormulaC15H24N2O
Molecular Weight248.37
refractive index1,536
Hazard Xn: Harmful;
Risk R20/21/22
Safety
Hazard Codes: Xn? 
Risk Statements: 20/21/22-37/38-41-48
20/21/22: Harmful by inhalation, in contact with skin and if swallowed?
37/38: Irritating to respiratory system and skin
41: Risk of serious damage to eyes?
48: Danger of serious damage to health by prolonged exposure????
Safety Statements: 22-26-36/37/39-45
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39: Wear suitable protective clothing, gloves and eye/face protection??
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intramuscular |
74150ug/kg (74.15mg/kg) |
? |
Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. |
| mouse |
LD50 |
intraperitoneal |
150mg/kg (150mg/kg) |
? |
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 18, Pg. 214, 1987. |
| mouse |
LD50 |
intravenous |
64850ug/kg (64.85mg/kg) |
? |
Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. |
| rat |
LD50 |
intraperitoneal |
125mg/kg (125mg/kg) |
? |
Chemical and Pharmaceutical Bulletin. Vol. 18, Pg. 2555, 1970.
? |
