|
bird - wild
|
LD50
|
oral
|
5620ug/kg (5.62mg/kg)
|
|
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
|
|
dog
|
LDLo
|
intravenous
|
760ug/kg (0.76mg/kg)
|
blood: leukopenia
blood: agranulocytosis
blood: other changes
|
Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 203, 1965.
|
|
man
|
TDLo
|
parenteral
|
631ug/kg (0.631mg/kg)
|
peripheral nerve and sensation: paresthesis
blood: changes in bone marrow not included above
|
Cancer Vol. 38, Pg. 1471, 1976.
|
|
monkey
|
LDLo
|
intravenous
|
1500ug/kg (1.5mg/kg)
|
blood: leukopenia
blood: agranulocytosis
blood: other changes
|
Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 203, 1965.
|
|
mouse
|
LD50
|
intramuscular
|
11500ug/kg (11.5mg/kg)
|
|
Pharmaceutical Chemistry Journal Vol. 17, Pg. 353, 1983.
|
|
mouse
|
LD50
|
intraperitoneal
|
11mg/kg (11mg/kg)
|
|
Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. Vol. 22, Pg. 36, 1990.
|
|
mouse
|
LD50
|
intravenous
|
14500ug/kg (14.5mg/kg)
|
|
Journal of Antibiotics, Series A. Vol. 13, Pg. 19, 1960.
|
|
mouse
|
LD50
|
oral
|
38mg/kg (38mg/kg)
|
peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
behavioral: ataxia
behavioral: somnolence (general depressed activity)
|
"Imifos," Giller, S.A., ed., Izd, Riga, USSR, 1968Vol. -, Pg. 129, 1968.
|
|
mouse
|
LD50
|
subcutaneous
|
16500ug/kg (16.5mg/kg)
|
liver: "hepatitis (hepatocellular necrosis), zonal"
blood: changes in spleen
kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"
|
Farmakologiya i Toksikologiya Vol. 8, Pg. 73, 1973.
|
|
quail
|
LD50
|
oral
|
237mg/kg (237mg/kg)
|
|
Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982.
|
|
rabbit
|
LD50
|
intravenous
|
5500ug/kg (5.5mg/kg)
|
liver: "hepatitis (hepatocellular necrosis), zonal"
kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)"
blood: changes in spleen
|
Farmakologiya i Toksikologiya Vol. 8, Pg. 73, 1973.
|
|
rat
|
LD50
|
intraarterial
|
8750ug/kg (8.75mg/kg)
|
|
Toxicology and Applied Pharmacology. Vol. 4, Pg. 344, 1962.
|
|
rat
|
LD50
|
intraperitoneal
|
8mg/kg (8mg/kg)
|
|
Clinical Proceedings of the Children's Hospital of the District of Columbia. Vol. 18, Pg. 307, 1962.
|
|
rat
|
LD50
|
intravenous
|
9400ug/kg (9.4mg/kg)
|
|
Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 1, 1958.
|
|
rat
|
LD50
|
oral
|
23mg/kg (23mg/kg)
|
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
|
|
rat
|
LD50
|
subcutaneous
|
7800ug/kg (7.8mg/kg)
|
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759,
|
