Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, hydrochloride (1:1) cas no:52-26-6

NameMorphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, hydrochloride (1:1)
CAS52-26-6
SynonymsMorphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, hydrochloride (9CI); Morphinan-3,6a-diol, 7,8-didehydro-4,5a-epoxy-17-methyl-, hydrochloride (8CI); (-)-Morphinehydrochloride; Ampek; Epimore; Morphine chlorhydrate; Morphine hydrochloride;Morphine monohydrochloride; Opso; Pacif; Pacif capsules; Theba-Intran;Thebametten
EINECS(EC#)200-136-2
Molecular FormulaC17H19 N O3 . Cl H
Molecular Weight321.83

storage temp−20°C

Hazard F,T
Risk 11-23/24/25-39/23/24/25
Safety

Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NO_x and HCl. See also (−)-MORPHINE.
Hazard Codes: 
F: Flammable
T: Toxic
Risk Statements:
R11: Highly flammable. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R39/23/24/25: Danger of very serious irreversible effects and toxic by inhalation, in contact with skin and if swallowed.
Safety Statements:
S7: Keep container tightly closed. 
S16: Keep away from sources of ignition.
S24: Avoid contact with skin.
S33: Take precautionary measures against static discharges.
S36/37: Wear suitable protective clothing and gloves.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1230 3/PG 2
WGK Germany: 1

1.		orl-rat LD50:335 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
2.		scu-rat LD50:480 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
3.		ivn-rat LD50:265 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
4.		orl-mus LD50:745 mg/kg		JJPAAZ    Japanese Journal of Pharmacology. 18 (1968),406.
5.		ipr-mus LD50:148 mg/kg		BJPCBM    British Journal of Pharmacology. 73 (1981),887.
6.		scu-mus LD50:354 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1787.
7.		ivn-mus LD50:180 mg/kg		ATSUDG    Archives of Toxicology, Supplement. 7 (1984),90.
8.		par-mus LD50:440 mg/kg		WKMRAH    Wakayama Medical Report. 24 (4)(1983),65.
9.		ivn-dog LD50:175 mg/kg		CPBTAL    Chemical and Pharmaceutical Bulletin. 7 (1959),372.