L-Cysteine cas no:52-90-4
Synonyms: L-Cysteine Free Base;2-Amino-3-mercapto-, (R)-;L-Cysteine (JAN);L-Cysteine Base/Hcl (mono/anhyd);(2R)-2-amino-3-mercaptopropanoic acid;Valine,3-mercapto-;alpha-Amino-beta-mercaptopropionic acid, L-;alpha-Amino-beta-thiolpropionic acid, L-;L-2-Amino-3-mercaptopropanoic acid;(2R)-2-amino-3-sulfanyl-propanoic acid;Half-cystine;L-2-Amino-3-mercaptopropionic acid;L-Cysteine Base;(+)-2-Amino-3-mercaptopropionic acid;H-Cys-OH;
NameL-Cysteine
CAS52-90-4
SynonymsL-Cysteine Free Base;2-Amino-3-mercapto-, (R)-;L-Cysteine (JAN);L-Cysteine Base/Hcl (mono/anhyd);(2R)-2-amino-3-mercaptopropanoic acid;Valine,3-mercapto-;alpha-Amino-beta-mercaptopropionic acid, L-;alpha-Amino-beta-thiolpropionic acid, L-;L-2-Amino-3-mercaptopropanoic acid;(2R)-2-amino-3-sulfanyl-propanoic acid;Half-cystine;L-2-Amino-3-mercaptopropionic acid;L-Cysteine Base;(+)-2-Amino-3-mercaptopropionic acid;H-Cys-OH;
EINECS(EC#)200-158-2
Molecular FormulaC3H7NO2S
Molecular Weight121.15
AppearanceWhite crystalline powder
alpha8.75 o (C=12, 2N HCL)
refractive index8.8 ° (C=8, 1mol/L HCl)
storage tempStore at RT.
Sensitive Air Sensitive
Hazard Xn:Harmful
Risk R22;R36/37/38
Safety Hazard Codes:Xn,Xi
Risk Statements:22-36/37/38-20/21/22
22:Harmful if swallowed
36/37/38:Irritating to eyes, respiratory system and skin
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:36-37/39-26
36:Wear suitable protective clothing
37/39:Wear suitable protective clothing, gloves and eye/face
protection
26:In case of contact with eyes, rinse immediately with plenty
of water and seek medical advice
WGK Germany:3
HS Code:29309012
Hazardous Substances Data:52-90-4(Hazardous Substances Data)
HS Code 29309012
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA1600000
- CHEMICAL NAME :
- Cysteine, L-
- CAS REGISTRY NUMBER :
- 52-90-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 31
- MOLECULAR FORMULA :
- C3-H7-N-O2-S
- MOLECULAR WEIGHT :
- 121.17
- WISWESSER LINE NOTATION :
- QVYZ1SH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1890 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1620 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1550 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 660 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1360 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 gm/kg/30D-C
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle weakness
Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 308 gm/kg/26W-I
- TOXIC EFFECTS :
- Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 gm/kg/30D-C
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Endocrine - other changes
Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3600 mg/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - physical
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 27600 mg/kg
- SEX/DURATION :
- female 23 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- male 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 68,351,1979
*** REVIEWS ***
TOXICOLOGY REVIEW
DPIRDU Dangerous Properties of Industrial Materials Report. (Van Nostrand
Reinhold, 115 Fifth Ave., New York, NY 10003) V.1- 1981-
Volume(issue)/page/year: 3(1),14,1983
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 2 mg/m3 JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4773
No. of Facilities: 81 (estimated)
No. of Industries: 2
No. of Occupations: 7
No. of Employees: 8402 (estimated)
No. of Female Employees: 7734 (estimated)
