supplier list
- Hangzhou Dingyuan Chemical Co.,Ltd.
- Tel:86-571-69829639
- Address: Room1202,the first building,Baiyun Mansion,Jianggan District
- Boc Sciences
- Tel:1-631-5046093
- Address: 45-16 Ramsey Road, Shirley, NY 11967, USA
Safety
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx and SOx.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| guinea pig | LD50 | oral | 3860mg/kg (3860mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| guinea pig | LD50 | subcutaneous | 182mg/kg (182mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | intraperitoneal | 112mg/kg (112mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1423, 1969. | |
| mouse | LD50 | intravenous | 17400ug/kg (17.4mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | oral | 1360mg/kg (1360mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | subcutaneous | 436mg/kg (436mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rabbit | LD50 | intramuscular | 500mg/kg (500mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rabbit | LD50 | oral | 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | intraperitoneal | 222mg/kg (222mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1423, 1969. | |
| rat | LD50 | intravenous | 26mg/kg (26mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | oral | 5080mg/kg (5080mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | subcutaneous | 2400mg/kg (2400mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
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