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Safety
Poison by intravenous, intraperitoneal, subcutaneous, and intramuscular routes. An experimental teratogen. Experimental reproductive effects. An antibiotic. When heated to decomposition Micronomicin (CAS NO.52093-21-7) emits toxic fumes of NOx.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intramuscular | 459mg/kg (459mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
mouse | LD50 | intramuscular | 245mg/kg (245mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. |
mouse | LD50 | intraperitoneal | 273mg/kg (273mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
mouse | LD50 | intravenous | 75mg/kg (75mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
mouse | LD50 | oral | 15600mg/kg (15600mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
mouse | LD50 | subcutaneous | 350mg/kg (350mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
rat | LD50 | intramuscular | 625mg/kg (625mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
rat | LD50 | intraperitoneal | 699mg/kg (699mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
rat | LD50 | intravenous | 104mg/kg (104mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. | |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982. | |
rat | LD50 | subcutaneous | 1223mg/kg (1223mg/kg) | Japanese Journal of Antibiotics. Vol. 30, Pg. 386, 1977. |
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