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Cinchonan-9-ol,6'-ethoxy-10,11-dihydro-, (8a,9R)- cas no:522-60-1

Synonyms: Hydrocinchonidine,6'-ethoxy- (7CI); Hydrocupreine, O6'-ethyl- (8CI); Hydrocupreine, ethyl ether(6CI); Ethylhydrocupreine; Numoquin; Optichin; Optochin

Identification
NameCinchonan-9-ol,6'-ethoxy-10,11-dihydro-, (8a,9R)-
CAS522-60-1
SynonymsHydrocinchonidine,6'-ethoxy- (7CI); Hydrocupreine, O6'-ethyl- (8CI); Hydrocupreine, ethyl ether(6CI); Ethylhydrocupreine; Numoquin; Optichin; Optochin
EINECS(EC#)208-333-5
Molecular FormulaC21H28 N2 O2
Molecular Weight340.51
Chemical Properties
refractive index1.618
storage temp2-8°C
Safety Data

Hazard Xn
Risk 22
Safety

Poison by ingestion and subcutaneous routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also ETHERS.

Hazard Codes HarmfulXn
Risk Statements 22
R22: Hydrocupreine ethyl ether (CAS NO.522-60-1) is harmful if swallowed.
WGK Germany 3
RTECS MW5950000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo oral 400mg/kg (400mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
mouse LDLo subcutaneous 24mg/kg (24mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

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