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2H-Furo[2,3-h]-1-benzopyran-2-one cas no:523-50-2

Synonyms: Isopsoralen(6CI);2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, d-lactone;Angecin;Angelicin (coumarin derivative);Furo[2,3-h]coumarin;Furo[5',4':7,8]coumarin;NSC 404563;Isopsoralen;

Identification
Name2H-Furo[2,3-h]-1-benzopyran-2-one
CAS523-50-2
SynonymsIsopsoralen(6CI);2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, d-lactone;Angecin;Angelicin (coumarin derivative);Furo[2,3-h]coumarin;Furo[5',4':7,8]coumarin;NSC 404563;Isopsoralen;
EINECS(EC#)201-480-6
Molecular FormulaC11H6O3
Molecular Weight186.16
Chemical Properties
AppearanceWhite Solid
refractive index1.667
storage temp2-8°C
Safety Data

Hazard Xn:Harmful;
Risk R20/21/22;R36/37/38;R40
Safety

Poison by ingestion and intraperitoneal routes. Questionable carcinogen. Mutation data reported. A tranquilizer, sedative, and anticonvulsant. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety information of 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran (523-50-2):
Hazard Codes  Xn,Xi
Risk Statements 
20/21/22  Harmful by inhalation, in contact with skin and if swallowed
36/37/38  Irritating to eyes, respiratory system and skin
40  Limited evidence of a carcinogenic effect
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39  Wear suitable protective clothing, gloves and eye/face protection
WGK Germany  3
RTECS  LV0940000


Toxicity
1.    

mmo-esc 40 mg/L

    MUREAV    Mutation Research. 58 (1978),23.
2.    

mmo-smc 50 µmol/L

    BUCABS    Bulletin du Cancer. 67 (1980),245.
3.    

orl-rat LD50:322 mg/kg

    IJMRAQ    Indian Journal of Medical Research. 63 (1975),833.
4.    

ipr-rat LD50:165 mg/kg

    IJMRAQ    Indian Journal of Medical Research. 63 (1975),833.
5.    

ipr-mus LD50:254 mg/kg

    IJMRAQ    Indian Journal of Medical Research. 63 (1975),833.

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CFM Oskar Tropitzsch
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Shanghai Huatuo Medical Science Co., Ltd.
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Kouting Chemical Co.,Ltd
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shanghai Tauto Biotech Co., Ltd
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ZHONGSHAN PHARMCARE BIOTECH CO.,LTD
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Boc Sciences
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Shanghai Forever Synthesis Co.,Ltd.
Tel:86-21-61124658
Address: Nianjiabang Rd, Pudong, Shanghai

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