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1,3-Benzodioxole,4,7-dimethoxy-5-(2-propen-1-yl)- cas no:523-80-8

Synonyms: 1,3-Benzodioxole,4,7-dimethoxy-5-(2-propenyl)- (9CI);Apiole (6CI);Benzene,1-allyl-2,5-dimethoxy-3,4-(methylenedioxy)- (7CI,8CI);1,2-Methylenedioxy-3,6-dimethoxy-4-allylbenzene;1-Allyl-2,5-dimethoxy-3,4-methylenedioxybenzene;4,7-Dimethoxy-5-(2-propenyl)-1,3-benzodioxole;5-Allyl-4,7-dimethoxy-1,3-benzodioxole; Apiol;Apioline;NSC 9070;Parsleyapiole;Parsley camphor;Petersilienapiol

Identification
Name1,3-Benzodioxole,4,7-dimethoxy-5-(2-propen-1-yl)-
CAS523-80-8
Synonyms1,3-Benzodioxole,4,7-dimethoxy-5-(2-propenyl)- (9CI);Apiole (6CI);Benzene,1-allyl-2,5-dimethoxy-3,4-(methylenedioxy)- (7CI,8CI);1,2-Methylenedioxy-3,6-dimethoxy-4-allylbenzene;1-Allyl-2,5-dimethoxy-3,4-methylenedioxybenzene;4,7-Dimethoxy-5-(2-propenyl)-1,3-benzodioxole;5-Allyl-4,7-dimethoxy-1,3-benzodioxole; Apiol;Apioline;NSC 9070;Parsleyapiole;Parsley camphor;Petersilienapiol
EINECS(EC#)208-349-2
Molecular FormulaC12H14 O4
Molecular Weight222.26
Chemical Properties
refractive index1.53
Safety Data

Risk 36/37/38
Safety

Moderately toxic by subcutaneous route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALLYL COMPOUNDS.Safety information of Apiole (CAS NO.523-80-8):
Risk Statements  36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements  26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 1515mg/kg (1515mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 35, Pg. 342, 1895.
mouse LDLo subcutaneous 1gm/kg (1000mg/kg)   Bolletino della Societe Italiana di Biologia Sperimentale. Vol. 14, Pg. 291, 1939.

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Boc Sciences
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