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Benzamide,2-hydroxy-N-(4-hydroxyphenyl)- cas no:526-18-1

Synonyms: Osalmid;2-Hydroxy-N-(4-hydroxyphenyl)benzamide;4'-Hydroxysalicylanilide;Auxobil;BRN 2941480;Bilene;Bilocol;Hydroxyphenyl salicylamide;N'-Salicyloyl-p-aminophenol;N-(4-Hydroxyphenyl)salicylamide;NSC 93960;Oksafenamid;Salmidochol;UNII-89741L759Z;p-Hydroxyphenylsalicylamide;Benzamide, 2-hydroxy-N-(4-hydroxyphenyl)- (9CI);Salicylanilide, 4'-hydroxy-;

Identification
NameBenzamide,2-hydroxy-N-(4-hydroxyphenyl)-
CAS526-18-1
SynonymsOsalmid;2-Hydroxy-N-(4-hydroxyphenyl)benzamide;4'-Hydroxysalicylanilide;Auxobil;BRN 2941480;Bilene;Bilocol;Hydroxyphenyl salicylamide;N'-Salicyloyl-p-aminophenol;N-(4-Hydroxyphenyl)salicylamide;NSC 93960;Oksafenamid;Salmidochol;UNII-89741L759Z;p-Hydroxyphenylsalicylamide;Benzamide, 2-hydroxy-N-(4-hydroxyphenyl)- (9CI);Salicylanilide, 4'-hydroxy-;
EINECS(EC#)208-385-9
Molecular FormulaC13H11NO3
Molecular Weight229.23
Chemical Properties
AppearanceWhite crystal
refractive index1.71
Safety Data

Hazard Xn
Risk R22
Safety

Safety Information of Osalmid (526-18-1):
Hazard Codes: Xn
Risk Statements: 22-36/37/38-42/43
22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
42/43: May cause sensitization by inhalation and skin contact
Safety Statements: 26-36/37
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37: Wear suitable protective clothing and gloves
Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.


Toxicity
1.    

orl-rat LD50:6702 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
2.    

ipr-rat LD50:1621 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
3.    

orl-mus LD50:1050 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 22 (1972),235.
4.    

ipr-mus LD50:517 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
5.    

scu-mus LD50:1900 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 116 (1958),154.
6.    

ivn-mus LD50:180 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#03234 .

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