Permethrin (3-(2,2-Dichloroethenyl)-2,2- dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl)methyl ester) cas no:52645-53-1

NamePermethrin (3-(2,2-Dichloroethenyl)-2,2- dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl)methyl ester)
CAS52645-53-1
SynonymsCorsair;Spartan (pesticide);Mitin BC;Coopex;InsomniaInsorbcid MP;Ecsumin;Dragnet;Ectiban;Cyclopropanecarboxylic acid,3-(2,2-dichloroethenyl)-2,2-dimethyl-,(3-phenoxyphenyl)methyl ester;Riapan A;NIA 33297;S 3151;FMC 41655;Exmin;SBP 15131TEC;Damminix;Ipitox;Perigen;Perigen W;KaleCollards are also indexed at this headingKaleait;Pounce;Stomoxys calcitransStablefly is also indexed at this headingStomozan;Efmethrin;MP 79;KestrelThis heading is used only when the specific taxonomycannot be established from the original documentKestrel (pesticide);NRDC 143;Chinetrin;Pertrin E;Stomoxin;SBP 1513;Imperator;Kavil;Bematin 987;JF 7065;ICI-PP 557;Cooper;(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethyl-cyclopropane-1-carboxylate;Anomethrin N;WL 43479;Kudos;Permasect;FMC 33297;Permanone;PP 557;Diffusil H;Adion;m-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate;NDRC-143;AI3-29158;D-Tetramethrin;Permethrin 95%TC, 25%WP, 50%WP, 25%EC;Permethrin;
EINECS(EC#)258-067-9
Molecular FormulaC₂₁H₂₀Cl₂O₃
Molecular Weight391.29

Appearancecolourless crystals (but the technical productis normally supplied as a pale brown liquid)
storage temp0-6°C

Hazard Xn: Harmful;N: Dangerous for the environment;T: Toxic;F: Flammable;
Risk R20/22
Safety

Poison by inhalation, intravenous, and intracerebral routes. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. A skin irritant. When heated to decomposition it emits toxic fumes of Cl^?. See also ESTERS.
Hazard Codes:?Xn,N,T,F
Risk Statements: 20/22-43-50/53-39/23/24/25-23/24/25-11-51/53-36-20/21/22?
R20/22:Harmful by inhalation and if swallowed.?
R43:May cause sensitization by skin contact.?
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R39:Danger of very serious irreversible effects.?
R11:Highly flammable.?
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R36:Irritating to eyes.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 13-24-36/37/39-60-61-45-36/37-16-7-26?
S13:Keep away from food, drink and animal foodstuffs.?
S24:Avoid contact with skin.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S60:This material and its container must be disposed of as hazardous waste.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.?
S16:Keep away from sources of ignition.?
S7:Keep container tightly closed.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN1230 3/PG 2
RTECS: GZ1255000

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - domestic	LD50	oral	32gm/kg (32000mg/kg)	?	Defense des Vegetaux. Vol. 32, Pg. 168, 1978.
chicken	LD50	oral	7gm/kg (7000mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: IRRITABILITY GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	JAT, Journal of Applied Toxicology. Vol. 7, Pg. 367, 1987.
duck	LD50	oral	11300mg/kg (11300mg/kg)	?	Defense des Vegetaux. Vol. 32, Pg. 168, 1978.
guinea pig	LD50	oral	4gm/kg (4000mg/kg)	?	"Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A316, Pg. 1984,
man	LD50	unreported	> 4gm/kg (4000mg/kg)	?	Defense des Vegetaux. Vol. 32, Pg. 168, 1978.
man	TDLo	oral	2270mg/kg (2270mg/kg)	BEHAVIORAL: COMA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Journal of Toxicology, Clinical Toxicology. Vol. 36, Pg. 57, 1998.
mouse	LC50	inhalation	685mg/m3 (685mg/m3)	?	Yakkyoku. Pharmacy. Vol. 30, Pg. 1635, 1979.
mouse	LD50	intraperitoneal	429mg/kg (429mg/kg)	?	Ecotoxicology and Environmental Safety. Vol. 18, Pg. 27, 1989.
mouse	LD50	intravenous	31mg/kg (31mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 66, Pg. 153, 1982.
mouse	LD50	oral	424mg/kg (424mg/kg)	?	Ecotoxicology and Environmental Safety. Vol. 18, Pg. 27, 1989.
mouse	LD50	skin	> 10gm/kg (10000mg/kg)	?	Yakkyoku. Pharmacy. Vol. 30, Pg. 1635, 1979.
mouse	LD50	subcutaneous	10gm/kg (10000mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA	Bochu Kagaku. Scientific Pest Control. Vol. 41, Pg. 143, 1976.
mouse	LD50	unreported	680mg/kg (680mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA BEHAVIORAL: ATAXIA	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(9), Pg. 69, 1988.
mouse	LDLo	intracrebral	600ug/kg (0.6mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 66, Pg. 290, 1982.
quail	LD50	oral	13500mg/kg (13500mg/kg)	?	Defense des Vegetaux. Vol. 32, Pg. 168, 1978.
rabbit	LD50	oral	4gm/kg (4000mg/kg)	?	"Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A316, Pg. 1984,
rabbit	LD50	skin	> 2gm/kg (2000mg/kg)	?	Farm Chemicals Handbook. Vol. -, Pg. C233, 1991.
rat	LC50	inhalation	485mg/m3 (485mg/m3)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(12), Pg. 21, 1990.
rat	LD	intravenous	> 270mg/kg (270mg/kg)	?	Nature. Vol. 246, Pg. 169, 1973.
rat	LD50	oral	383mg/kg (383mg/kg)	?	National Technical Information Service. Vol. AD-A047-284,
rat	LD50	skin	1750mg/kg (1750mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(9), Pg. 69, 1988.
rat	LD50	subcutaneous	6600mg/kg (6600mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA	Bochu Kagaku. Scientific Pest Control. Vol. 41, Pg. 143, 1976.
rat	LD50	unreported	537mg/kg (537mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA BEHAVIORAL: COMA	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(9), Pg. 69, 1988.