Pregn-4-ene-3,11,20-trione,17,21-dihydroxy- cas no:53-06-5
Synonyms: Cortisone(8CI); 11-Dehydro-17-hydroxycorticosterone;17,21-Dihydroxypregn-4-ene-3,11,20-trione; 17-Hydroxy-11-dehydrocorticosterone;17a,21-Dihydroxy-4-pregnene-3,11,20-trione;17a,21b-Dihydroxy-4-pregnene-3,11,20-trione; 17a-Hydroxy-11-dehydrocorticosterone;Adrenalex; Compound E; Cortisate; Cortivite; Cortogen; Cortone; KE; Kendall'scompound E; NSC 9703; Pregn-4-en-17a,21-diol-3,11,20-trione; Reichstein's substance Fa; Wintersteiner'scompound F; D4-Pregnene-17a,21-diol-3,11,20-trione
NamePregn-4-ene-3,11,20-trione,17,21-dihydroxy-
CAS53-06-5
SynonymsCortisone(8CI); 11-Dehydro-17-hydroxycorticosterone;17,21-Dihydroxypregn-4-ene-3,11,20-trione; 17-Hydroxy-11-dehydrocorticosterone;17a,21-Dihydroxy-4-pregnene-3,11,20-trione;17a,21b-Dihydroxy-4-pregnene-3,11,20-trione; 17a-Hydroxy-11-dehydrocorticosterone;Adrenalex; Compound E; Cortisate; Cortivite; Cortogen; Cortone; KE; Kendall'scompound E; NSC 9703; Pregn-4-en-17a,21-diol-3,11,20-trione; Reichstein's substance Fa; Wintersteiner'scompound F; D4-Pregnene-17a,21-diol-3,11,20-trione
EINECS(EC#)200-162-4
Molecular FormulaC21H28 O5
Molecular Weight360.4492
AppearanceOff-white crystalline powder
refractive index210 ° (C=1, EtOH)
storage temp-20°C Freezer
Hazard Damaging side effects, e.g., sodium retention from ingestion.
Safety
Human teratogenic effects by ingestion and possibly other routes: developmental abnormalities of the eye and ear, craniofacial area, musculoskeletal system, cardiovascular system and other neonatal measures or effects. Other experimental teratogenic effects. Additional reproductive effects in experimental animals. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
Safety Statements: 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: GM9020000
F: 18
F18: Must be handled by instructed people only.
| 1. |
|
dns-rat-scu 168 mg/kg/3D-C
|
|
ENDOAO Endocrinology (Baltimore). 94 (1974),1637. |
| 2. |
|
dnd-mus:lvr 100 µmol/L
|
|
ENZYAS Enzymologica. 41 (1971),183. |
