Ethanaminium,N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-, bromide (1:1) cas no:53-46-3

NameEthanaminium,N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-, bromide (1:1)
CAS53-46-3
SynonymsAmmonium,diethyl(2-hydroxyethyl)methyl-, bromide, xanthene-9-carboxylate (8CI);Diethyl(2-hydroxyethyl)methylammonium bromide, xanthene-9-carboxylate (7CI);Ethanaminium, N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-, bromide(9CI); Asabaine; Avagal; Banthin; Banthine; Banthine bromide; Doladene;Frenogastrico; Gastron; Gastrosedan; MTB 51; Mantheline; Metantyl; Metanyl;Metaxan; Methanide; Methantheline bromide; Methanthelinium bromide; Methanthinebromide; Methelina; Resobantin; SC 2910; Ulcine; Ulcudexter; Uldumont; Vagamin;Vagantin; Xanteline; b-Diethylaminoethyl xanthene-9-carboxylate methobromide
EINECS(EC#)200-176-0
Molecular FormulaC21H26 N O3 . Br
Molecular Weight420.39

Safety

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Unspecified human reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x, NH₃, and Br⁻.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	23mg/kg (23mg/kg)		Proceedings of the Society for Experimental Biology and Medicine. Vol. 78, Pg. 576, 1951.
dog	LDLo	oral	460mg/kg (460mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 104, Pg. 54, 1952.
mouse	LD50	intraperitoneal	46mg/kg (46mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 141, 1952.
mouse	LD50	intravenous	4300ug/kg (4.3mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 221, 1956.
mouse	LD50	oral	460mg/kg (460mg/kg)		Drugs in Japan Vol. 6, Pg. 357, 1982.
mouse	LDLo	subcutaneous	395mg/kg (395mg/kg)		United States Patent Document. Vol. #3714357,
rat	LD50	intravenous	4800ug/kg (4.8mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Toxicology and Applied Pharmacology. Vol. 1, Pg. 391, 1959.
rat	LD50	oral	400mg/kg (400mg/kg)		Proceedings of the Society for Experimental Biology and Medicine. Vol. 78, Pg. 708, 1951.
rat	LDLo	subcutaneous	320mg/kg (320mg/kg)		United States Patent Document. Vol. #3714357,