D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5) (salt) cas no:53179-09-2
Synonyms: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol;32385-11-8;Salvamina;Sisomicine [INN-French];Sch-13475;Sisomycin;O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-6))-2-deoxy-L-streptamine;Prestwick_847;Siseptin (TN);D-Streptamine,O-3-deoxy-4-C-methyl-3- (methylamino)-a-L-arabinopyranosyl-(1f6)- O-[2,6-diamino-2,3,4,6-tetradeoxy-R-Dglycero- hex-4-enopyranosyl-(1f4)]-2-deoxy-,sulfate (2:5) (salt);Baymicine;Sisomicin sulfate [USAN:JAN];
NameD-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5) (salt)
CAS53179-09-2
Synonyms(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol;32385-11-8;Salvamina;Sisomicine [INN-French];Sch-13475;Sisomycin;O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-6))-2-deoxy-L-streptamine;Prestwick_847;Siseptin (TN);D-Streptamine,O-3-deoxy-4-C-methyl-3- (methylamino)-a-L-arabinopyranosyl-(1f6)- O-[2,6-diamino-2,3,4,6-tetradeoxy-R-Dglycero- hex-4-enopyranosyl-(1f4)]-2-deoxy-,sulfate (2:5) (salt);Baymicine;Sisomicin sulfate [USAN:JAN];
EINECS(EC#)258-414-4
Molecular Formula2(C19H37N5O7).5(H2SO4)
Molecular Weight937.89
storage temp2-8°C
Hazard T,Xi
Risk 61-20/21/22-36/37/38
Safety
Poison by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. See also SULFATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes
T,
Xi
Risk Statements 61-20/21/22-36/37/38
R61:May cause harm to the unborn child.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 53-22-36/37/39-45-36-26
S22:Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S53:Avoid exposure - obtain special instructions before use.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 3
RTECS WK2288000
| 1. |
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scu-rat LD50:500 mg/kg
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JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 4 (1978),107. |
| 2. |
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ivn-rat LD50:49 mg/kg
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JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 4 (1978),107. |
| 3. |
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ims-rat LD50:404 mg/kg
|
|
JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 4 (1978),107. |
| 4. |
|
ipr-mus LD50:221 mg/kg
|
|
JANTAJ Journal of Antibiotics. 23 (1970),551. |
| 5. |
|
scu-mus LD50:272 mg/kg
|
|
JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 4 (1978),107. |
| 6. |
|
ivn-mus LD50:34 mg/kg
|
|
JANTAJ Journal of Antibiotics. 23 (1970),551. |
| 7. |
|
ims-mus LD50:280 mg/kg
|
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JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 4 (1978),107. |
