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Thiamine nitrate cas no:532-43-4

Synonyms: Thiaminenitrate (6CI);Thiamine nitrate (salt) (7CI,8CI);Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (salt) (9CI);3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,b-hydroxyethylthiazolium nitrate;Aneurine mononitrate;Aneurine-nitrate;Betabion mononitrate;Vitamin B1mononitrate;Vitamin B1 nitrate;Vitamin B1 mononitrate;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (1:1);Thiamine mononitrate;

Identification
NameThiamine nitrate
CAS532-43-4
SynonymsThiaminenitrate (6CI);Thiamine nitrate (salt) (7CI,8CI);Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (salt) (9CI);3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,b-hydroxyethylthiazolium nitrate;Aneurine mononitrate;Aneurine-nitrate;Betabion mononitrate;Vitamin B1mononitrate;Vitamin B1 nitrate;Vitamin B1 mononitrate;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (1:1);Thiamine mononitrate;
EINECS(EC#)208-537-4
Molecular FormulaC12H17N5O4S
Molecular Weight327.36 .
Chemical Properties
Appearancewhite crystal powder
Safety Data

Safety

Poison by intravenous and intraperitoneal routes. A powerful oxidizer. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Safety Statements of Thiamine mononitrate (CAS NO.532-43-4): 22-24/25
S22: Do not breathe dust.?
S24/25: Avoid contact with skin and eyes.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 350mg/kg (350mg/kg) ? Drugs in Japan Vol. 6, Pg. 449, 1982.
mouse LD oral > 5gm/kg (5000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 114, 1992.
mouse LD50 intraperitoneal 387mg/kg (387mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 153, 1948.
mouse LD50 intravenous 84mg/kg (84mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 153, 1948.
rabbit LD50 intravenous 113mg/kg (113mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 153, 1948.
rabbit LD50 intravenous 300mg/kg (300mg/kg) ? Drugs in Japan Vol. 6, Pg. 449, 1982.

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