4-Quinolinemethanol, α-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,(aS)-rel- cas no:53230-10-7
Synonyms: 4-Quinolinemethanol,a-2-piperidinyl-2,8-bis(trifluoromethyl)-,(R*,S*)-(?à)-;(?à)-Mefloquine;4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-,(R*,S*)-;Lariam;Mefloquin;Mefloquine;Mephaquin;Racemic mefloquine;Ro21-5998;WR 142490;? Mefloquine;
Name4-Quinolinemethanol, α-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,(aS)-rel-
CAS53230-10-7
Synonyms4-Quinolinemethanol,a-2-piperidinyl-2,8-bis(trifluoromethyl)-,(R*,S*)-(?à)-;(?à)-Mefloquine;4-Quinolinemethanol, a-2-piperidinyl-2,8-bis(trifluoromethyl)-,(R*,S*)-;Lariam;Mefloquin;Mefloquine;Mephaquin;Racemic mefloquine;Ro21-5998;WR 142490;? Mefloquine;
Molecular FormulaC17H16F6N2O
Molecular Weight378.31
refractive index1.519
storage tempRefrigerator, Under Inert Atmosphere
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VC0333400
- CHEMICAL NAME :
- 4-Quinolinemethanol,
alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-,
(R*,S*)-(+-)-
- CAS REGISTRY NUMBER :
- 53230-10-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H16-F6-N2-O
- MOLECULAR WEIGHT :
- 378.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 25 mg/kg/5W-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Musculoskeletal - joints
Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200
Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year:
123,894,1995
