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Benzenemethanol, a-(aminomethyl)-3-hydroxy- cas no:536-21-0

Synonyms: Benzylalcohol, a-(aminomethyl)-m-hydroxy-(6CI,8CI); (?à)-Norfenefrine;(?à)-Norphenylephrine; (?à)-m-Octopamine; 1-(3-Hydroxyphenyl)-2-aminoethanol;1-(m-Hydroxyphenyl)-2-aminoethanol; 2-Amino-1-(3-hydroxyphenyl)ethanol;3-[2-Amino-1-hydroxyethyl]phenol; DL-1-(3-Hydroxyphenyl)-2-aminoethanol;DL-Norphenylephrine; DL-m-Octopamine; Metacardiol; Metaoctopamine; Norfenefrine;Normetasympathol; Normetasynephrine; Normetol; Normezaton; Norphenephrine;Norphenylephrine; [2-Hydroxy-2-(3-hydroxyphenyl)ethyl]amine;dl-1-(m-Hydroxyphenyl)-2-aminoethanol; dl-m-Octopamine;m-Hydroxyphenylethanolamine; m-Octopamine; p-Hydroxynoradrenaline; a-(Aminomethyl)-m-hydroxybenzylalcohol

Identification
NameBenzenemethanol, a-(aminomethyl)-3-hydroxy-
CAS536-21-0
SynonymsBenzylalcohol, a-(aminomethyl)-m-hydroxy-(6CI,8CI); (?à)-Norfenefrine;(?à)-Norphenylephrine; (?à)-m-Octopamine; 1-(3-Hydroxyphenyl)-2-aminoethanol;1-(m-Hydroxyphenyl)-2-aminoethanol; 2-Amino-1-(3-hydroxyphenyl)ethanol;3-[2-Amino-1-hydroxyethyl]phenol; DL-1-(3-Hydroxyphenyl)-2-aminoethanol;DL-Norphenylephrine; DL-m-Octopamine; Metacardiol; Metaoctopamine; Norfenefrine;Normetasympathol; Normetasynephrine; Normetol; Normezaton; Norphenephrine;Norphenylephrine; [2-Hydroxy-2-(3-hydroxyphenyl)ethyl]amine;dl-1-(m-Hydroxyphenyl)-2-aminoethanol; dl-m-Octopamine;m-Hydroxyphenylethanolamine; m-Octopamine; p-Hydroxynoradrenaline; a-(Aminomethyl)-m-hydroxybenzylalcohol
EINECS(EC#)208-626-8
Molecular FormulaC8H11 N O2
Molecular Weight153.20
Chemical Properties
refractive index1.614
Safety Data

Safety

Poison by ingestion,subcutaneous,intravenous,and intraperitoneal routes.When heated to decomposition, 3-(2-Amino-1-hydroxyethyl) phenol (CAS NO.536-21-0) emits toxic fumes of NOx.


Toxicity
1.    

orl-rat LD50:390 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),217.
2.    

ipr-rat LD50:32 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),217.
3.    

scu-rat LD50:28,100 µg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),60.
4.    

ivn-rat LD50:17,400 µg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),217.
5.    

orl-mus LD50:263 mg/kg

    RPOBAR    Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),295.
6.    

ipr-mus LD50:198 mg/kg

    RPOBAR    Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),295.
7.    

scu-mus LD50:459 mg/kg

    RPOBAR    Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),295.
8.    

ivn-mus LD50:4900 µg/kg

    RPOBAR    Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),295.

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