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1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1) cas no:536-43-6

Synonyms: 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (9CI);Propiophenone,4'-butoxy-3-piperidino-, hydrochloride (7CI,8CI);4'-Butoxy-3-piperidinopropiophenone hydrochloride;Diclonina;Diclonine;Dyclothane;Tanaclone;

Identification
Name1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1)
CAS536-43-6
Synonyms1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (9CI);Propiophenone,4'-butoxy-3-piperidino-, hydrochloride (7CI,8CI);4'-Butoxy-3-piperidinopropiophenone hydrochloride;Diclonina;Diclonine;Dyclothane;Tanaclone;
EINECS(EC#)208-633-6
Molecular FormulaC18H27NO2.HCl
Molecular Weight325.87
Chemical Properties
storage temp-20°C Freezer
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. A skin and severe eye irritant. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Safety information of Dyclonine hydrochloride (536-43-6):
Hazard Codes  Xn
Risk Statements 
22  Harmful if swallowed
37/38  Irritating to respiratory system and skin
41  Risk of serious damage to eyes
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36  Wear suitable protective clothing
RIDADR  3249
WGK Germany  3
RTECS  UG8750000
HazardClass  6.1(b)
PackingGroup  III


Toxicity
1.    

skn-rbt 1% MLD

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 137 (1962),410.
2.    

eye-rbt 1% MLD

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 137 (1962),410.
3.    

eye-rbt 2% SEV

    ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),708.
4.    

ipr-rat LD50:33 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),708.
5.    

scu-rat LD50:201 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 115 (1955),413.
6.    

orl-mus LDLo:100 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),616.
7.    

ipr-mus LD50:52 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 137 (1962),410.
8.    

scu-mus LD50:42 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 5 (1955),559.
9.    

ivn-mus LD50:20 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 115 (1955),419.
10.    

orl-dog LDLo:40 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),616.
 

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