2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (1:1) cas no:5370-01-4
Synonyms: 2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (9CI);Ethylamine, 1-methyl-2-(2,6-xylyloxy)-,hydrochloride (7CI,8CI);Katen;Ko 1173;Ko 1173Cl;Mexiletinehydrochloride;Mexilitene;Mexitil;Ritalmex;
Name2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (1:1)
CAS5370-01-4
Synonyms2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (9CI);Ethylamine, 1-methyl-2-(2,6-xylyloxy)-,hydrochloride (7CI,8CI);Katen;Ko 1173;Ko 1173Cl;Mexiletinehydrochloride;Mexilitene;Mexitil;Ritalmex;
EINECS(EC#)226-362-1
Molecular FormulaC11H17NO.HCl
Molecular Weight179.25878
Appearancewhite to off-white solid
storage temp2-8°C
Hazard Xn:Harmful;
Risk R22;R36/37/38
Safety
Poison by ingestion, subcutaneous, intramuscular, and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl. See also AMINES.
Hazard Codes:
Xn: Harmful .gif)
Risk Statements about Mexiletine hydrochloride (5370-01-4):
R22 Harmful if swallowed.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Mexiletine hydrochloride (5370-01-4):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 Wear suitable protective clothing.
| 1. |
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orl-rat LD50:330 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 2. |
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scu-rat LD50:500 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 3. |
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ivn-rat LD50:27 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 4. |
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ims-rat LD50:190 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 5. |
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orl-mus LD50:272 mg/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 38 (1988),1398. |
| 6. |
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scu-mus LD50:235 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 7. |
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ivn-mus LD50:21 mg/kg
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BLLIAX Bratislavske Lekarske Listy. 85 (1986),152. |
| 8. |
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ims-mus LD50:128 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),922. |
| 9. |
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orl-dog LD50:356 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 16 (1985),590. |
