1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)- cas no:53760-19-3

Name1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
CAS53760-19-3
Synonyms[11]Cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E,21R)-; 1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,[3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-; Cytochalasin H;Cytochalasin O; Kodocytochalasin 1; Paspalin P I
Molecular FormulaC30H39 N O5
Molecular Weight493.70

refractive index1.591
storage temp2-8°C

Hazardclass6.1(a)

Hazard T+
Risk 26/27/28-63
Safety

Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Hazard Codes T+
Risk Statements 26/27/28-63
R26/27/28: Paspalin (CAS NO.53760-19-3) is very toxic by inhalation, in contact with skin and if swallowed. 
R63:Possible risk of harm to the unborn child.
Safety Statements 28-36/37-45
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 3462 6.1/PG 2
WGK Germany 3
RTECS HA5306000
F 10
HazardClass 6.1(a)
PackingGroup I

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
chicken	LD50	oral	12500ug/kg (12.5mg/kg)		Canadian Journal of Microbiology. Vol. 22, Pg. 1137, 1976.
mammal (species unspecified)	LD50	intraperitoneal	2341ug/kg (2.341mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA	Indian Drugs. Vol. 15, Pg. 76, 1978.
mouse	LD50	intravenous	2mg/kg (2mg/kg)		"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 2, Pg. 439, 1980.
mouse	LDLo	unreported	2mg/kg (2mg/kg)		Japanese Journal of Experimental Medicine. Vol. 48, Pg. 105, 1978.