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Ethanamine,2-chloro-N-(2-chloroethyl)-N-ethyl- cas no:538-07-8

Synonyms: Triethylamine,2,2'-dichloro- (6CI,7CI,8CI); Bis(2-chloroethyl)ethylamine;Ethylbis(2-chloroethyl)amine; HN 1; HN 1 (chemical warfare agent);N,N-Bis(2-chloroethyl)ethanamine; N-Ethyl-N,N-bis(2-chloroethyl)amine;N-Ethylbis(2-chloroethyl)amine; Nitrogen mustard (HN 1)

Identification
NameEthanamine,2-chloro-N-(2-chloroethyl)-N-ethyl-
CAS538-07-8
SynonymsTriethylamine,2,2'-dichloro- (6CI,7CI,8CI); Bis(2-chloroethyl)ethylamine;Ethylbis(2-chloroethyl)amine; HN 1; HN 1 (chemical warfare agent);N,N-Bis(2-chloroethyl)ethanamine; N-Ethyl-N,N-bis(2-chloroethyl)amine;N-Ethylbis(2-chloroethyl)amine; Nitrogen mustard (HN 1)
Molecular FormulaC6H13 Cl2 N
Molecular Weight170.10
Chemical Properties
refractive index1.461
Safety Data

Safety

Deadly poison by inhalation, skin contact, ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of Cl and NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo skin 40mg/kg (40mg/kg)   National Technical Information Service. Vol. PB158-507,
mouse LD50 intraperitoneal 1030ug/kg (1.03mg/kg)   National Technical Information Service. Vol. PB158-507,
mouse LD50 skin 13mg/kg (13mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 91, Pg. 224, 1947.
mouse LD50 subcutaneous 1100ug/kg (1.1mg/kg)   National Technical Information Service. Vol. PB158-507,
rabbit LD50 intravenous 2mg/kg (2mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT
National Technical Information Service. Vol. PB158-507,
rabbit LD50 skin 15mg/kg (15mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 91, Pg. 224, 1947.
rat LD50 intravenous 500ug/kg (0.5mg/kg)   National Technical Information Service. Vol. PB158-507,
rat LD50 oral 2500ug/kg (2.5mg/kg)   National Technical Information Service. Vol. PB158-507,
rat LD50 skin 17mg/kg (17mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 91, Pg. 224, 1947.
rat LD50 unreported 500ug/kg (0.5mg/kg)   Pharmaceutical Bulletin. Vol. 1, Pg. 297, 1953.

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